T Cell Receptor (TCR) Vb 8.1, 8.2 Antikörper

Antigen: T Cell Receptor (TCR) Vb 8.1, 8.2

Klonalität: Monoklonal (KJ16)

Wirt: Ratte

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN255353

Produktbeschreibung

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: KJ16

Beschreibung: The receptors on T cells consist of immunoglobulin like integral membrane glycoproteinscontaining 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunithas, external to the cell membrane, an N terminal variable domain and a C terminalconstant domain.T cell receptors recognise foreign antigens which have been processed as smallpeptides and bound to major histocompatibility complex molecules at the surface ofantigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and onebeta chain or one delta and one gamma chain. In a single cell, the T cell receptor lociare rearranged and expressed in the order delta, gamma, beta, and alpha. If both deltaand gamma rearrangements produce functional chains, the cell expresses delta andgamma. If not, the cell proceeds to rearrange the beta and alpha loci. Alternate Names: anti-T cell receptor beta chain antibody, anti-T cell antigen receptor beta polypeptideantibody, anti-T cell receptor beta chain V region CTL L17 antibody, anti-T cell receptorbeta cluster antibody, anti-T cell receptor beta locus antibody, anti-TCRB antibody,anti-TRB antibody, anti-TRB@ antibody.

Spezifität: ABIN255353 recognises the V beta 8.1 and V beta 8.2 determinants of the murine Tcell receptor. Species Reactivity: Mouse. Not yet tested in other species. Localization: Plasma membrane.

Anwendungen

Konzentration: 0.2 mg/ml

Buffer: Phosphate buffered saline pH7.4. Preservative: 0.09% Sodium Azide (NaN3).

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Forschungsgebiet: Immunologie, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar