T-Cell Receptor (TCR), gamma/delta- Antikörper (PE)

Antigen: T-Cell Receptor (TCR), gamma/delta-

Klonalität: Monoklonal (V65)

Wirt: Maus

Reaktivität: Ratte (Rattus)

Konjugat: PE

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN255344

Produktbeschreibung

Weitere Bezeichnung: T Cell Receptor (TCR) gamma/delta

Immunogen: CD3 +ve TCR alpha/beta -ve rat T cell hybridoma line.

Isotyp: IgG1

Klon: V65

Beschreibung: The receptors on T cells consist of immunoglobulin like integral membrane glycoproteinscontaining 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunithas, external to the cell membrane, an N terminal variable domain and a C terminalconstant domain. T cell receptors recognize foreign antigens which have beenprocessed as small peptides and bound to major histocompatibility complex moleculesat the surface of antigen presenting cells. Each T cell receptor is a dimer consisting ofone alpha and one beta chain or one delta and one gamma chain. In a single cell, the Tcell receptor loci are rearranged and expressed in the order delta, gamma, beta, andalpha. If both delta and gamma rearrangements produce functional chains, the cellexpresses delta and gamma. If not, the cell proceeds to rearrange the beta and alphaloci. Alternate Names: anti-T cell antigen receptor delta polypeptide antibody, anti-T cell antigen receptorgamma polypeptide antibody, anti-T cell rearranging gene gamma antibody, anti-T cellreceptor delta antibody, anti-T cell receptor delta locus antibody, anti-T cell receptorgamma antibody, anti-T cell receptor gamma chain C region PT gamma 1/2 antibody,anti-T cell receptor gamma cluster antibody, anti-T cell receptor gamma locus antibody,anti-T cell receptor T3 delta chain antibody, anti-T cell receptors antibody, anti-T cellsurface glycoprotein CD3 delta chain antibody, anti-TCRD antibody, anti-TCRGantibody, anti-TRD antibody, anti-TRD locus antibody, anti-TRD@ antibody, anti-TRGantibody, anti-TRG locus antibody, anti-TRG@ antibody.

Spezifität: Recognizes a constant determinant of the rat gamma/delta T cell receptor. This antibodystains all rat gamma/delta T cells, and also identifies as gamma/delta T cells apopulation of dendritic epidermal T lymphocytes. Species Reactivity: Cross reacts with Rat.

Anwendungen

Buffer: Phosphate buffered saline pH7.2 lyophilised. Preservative: 0.09% Sodium Azide.

Lagerung: Store at 4C. Do not freeze.

Forschungsgebiet: Immunologie, Rezeptoren, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar