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CD247 Molecule (CD247) Antikörper (PE)
| Antigen | CD247 Molecule (CD247) |
| Synonyme | T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA, Cd3, T3z, Cd3h, Cd3z, TCRk, Tcrz, CD3-eta, CD3zeta, AW552088, CD3-zeta, 4930549J05Rik, A430104F18Rik, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023 |
| Klonalität | Monoklonal (G3) |
| Wirt |
 Alternativen Maus |
| Reaktivität |
Alternativen Human |
| Konjugat |
Alternativen PE |
| Applikation |
Alternativen Durchflusszytometrie (FACS)
|
| Produktnummer | ABIN254749 |
| Menge | 100 Tests |
| Preis | 480,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD247 / CD3Z |
| Gen-ID | 919 |
| Immunogen | 113 amino acid synthetic peptide corresponding to the cytoplasmic domain of murinezeta TCR subunit. |
| Isotyp | IgG2a |
| Klon | G3 |
| Beschreibung | Alternate Names: Anti-CD3 ZETA antibody, Anti-CD3H antibody, Anti-CD3Q antibody, Anti-CD3Zantibody, Anti-CD3Z antigen zeta polypeptide antibody, Anti-T cell receptor T3 zetachain antibody, Anti-T cell receptor zeta chain antibody, Anti-T cell surface glycoproteinCD3 zeta chain antibody, Anti-T3Z antibody, Anti-TCRZ antibody, Anti-TiT3 complexantibody. |
| Spezifität | The T cell antigen receptor (TCR) consists of a ligand-specific alpha/beta heterodimernon-covalently associated with five invariant chains including the CD3 gamma/delta/etaand zeta subunits, all of which are required for efficient surface expression. T cellactivation through the TCR induces cellular differentiation and/or proliferation and theproduction of lymphokines and cytokines. Both the CD3 and TCR zeta subunits areproposed to be responsible for the intracellular signal transduction events.A novel monoclonal antibody, named G3, has been developed that is specific for theTCR zeta chain subunit (CD247). The antibody is capable of precipitating bothnon-phosphorylated and tyrosine phosphorylated TCR zeta chain and may be used todetect TCR zeta expressing cells using flow cytometry on permeabilised cells. Species Reactivity: Human. Not yet tested in other species. Localization: Cell Membrane. |
Anwendungen
| Buffer | Phosphate buffered saline, pH7.2, 1% Bovine Serum Albumin. Preservative: 0.09% Sodium Azide. |
| Lagerung | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Forschungsgebiet | CD Antigene, Oberflächenrezeptoren der Immunzellen |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "CD247 Molecule (CD247)", Typ "Antikörper" finden
| Wirte | Maus (50), Hamster (40), Kaninchen (23) |
| Reaktivitäten | Maus (57), Human (48), Ratte (Rattus) (18), Affe (11), Huhn (7), Schwein (1), Schaf (1) |
| Applikationen | Durchflusszytometrie (FACS) (83), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (35), Western Blot (WB) (35), Immunpräzipitation (IP) (34), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), Enzyme Immunoassay (EIA) (17), Immunfluoreszenz (IF) (16), ELISA (7), Intrazelluläre Durchflusszytometrie (ICFC) (4), Immunzytochemie (ICC) (2), Abreicherung (Depletion) (1), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Funktionale Studien (Func) (1), Immunhistochemie (IHC) (1) |
| Konjugate | FITC (18), Biotin (11), PE (8), APC (2), APC,Cy7 (2), Alexa Fluor 488 (2), Alexa Fluor 647 (2), Alexa Fluor 700 (2), PE,Cy5 (2), PE,Cy7 (2), Pacific Blue (2), PerCP,Cy5.5 (2), RPE (1) |
| Epitope | C-Term (3), N-Term (1), pTyr142 (1) |
