Blood Group A Antigen Antikörper

Antigen: Blood Group A Antigen

Klonalität: Monoklonal (9A)

Wirt: Maus

Applikation: Enzyme Immunoassay (EIA), Immunpräzipitation (IP)

Produktnummer: ABIN251110

Produktbeschreibung

Immunogen: Cell preparation: A431 cells (human vulval squamous carcinoma cell line).

Isotyp: IgG3

Klon: 9A

Beschreibung: Blood-group antigens are generally defined as molecules formed by sequential additionof saccharides to the carbohydrate side chains of lipids and proteins detected onerythrocytes and certain epithelial cells. The A, B and H antigens are reported toundergo modulation during malignant cellular transformation. Blood group relatedantigens represent a group of carbohydrate determinants carried on both glycolipids andglycoproteins. They are usually mucin-type, and are detected on erythrocytes, certainepithelial cells, and in secretions of certain individuals. Sixteen genetically andbiosynthetically distinct but inter-related specificities belong to this group of antigens,including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chainantigens.

Spezifität: 9A is suitable for binding to the EGF receptor in A431 cells only. These cells have aglycosylation defect which reveals otherwise cryptic sugar structures. Species Reactivity: Cross-reacts with Human. Localization: Cell Membrane.

Anwendungen

Konzentration: 1 mg/ml

Buffer: PBS. Preservative: No Preservative.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Forschungsgebiet: Zell-/Gewebemarker, Blutgruppen-Antigene

Beschränkungen: Nur für Forschungszwecke einsetzbar