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Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) Antikörper

Antigen

Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27)

Synonyme APC3, HNUC, CDC27Hs, D0S1430E, D17S978E, wu:fb54g06, wu:fc88c12, AI452358, BC023187, MGC80529, CDC27, MGC145551, NV10210
Klonalität Monoklonal (AF3-1)
Wirt
Reaktivität
Alternativen

Human, Maus, Ratte (Rattus)

Applikation
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Immunpräzipitation (IP), Western Blot (WB)
Produktnummer ABIN251047
Menge 0.1 mg  (2 mg/ml)
Preis 350,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung CDC27
Gen-ID 996, 217232, 360643
Immunogen Synthetic peptide conjugated to KLH, corresponding to amino acids 814-823 of HumanCdc27.
Isotyp IgG2a  (Passende Sekundärantikörper)
Klon AF3-1
Beschreibung Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and thegene product of Schizosaccharomyces pombe nuc 2. It is a component of the AnaphasePromoting Complex (APC), which is composed of eight protein subunits and is highlyconserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitinconjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins.This protein and 3 other members of the APC complex contain the TPR(tetratricopeptide repeat), a protein domain important for protein protein interaction. Thisprotein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDCand BUBR1, and thus may be involved in controlling the timing of mitosis. Alternate Names: anti-Anaphase Promoting Complex 3 antibody, anti-Anaphase promoting complexprotein 3 antibody, anti-Anaphase Promoting Complex Subunit 3 antibody, anti-APC 3antibody, anti-APC3 antibody, anti-Cdc 27 antibody, anti-CDC27Hs antibody, anti-CellDivision Cycle 27 antibody, anti-Cell division cycle protein 27 homolog antibody,anti-D0S1430E antibody, anti-D17S978E antibody, anti-H NUC antibody, anti-HNUCantibody, anti-Nuc2 homolog antibody.
Spezifität Species Reactivity: Cross-reacts with Human, Mouse, Rat, Xenopus laevis, Cow and Dog.Not yet tested inother species. Localization: Nuclear.

Anwendungen

Applikationshinweise Western Blot 1 - 2 ug/ml
Konzentration 2 mg/ml
Buffer 0.01M PBS. pH 7.4
Lagerung Store at +4Degree C short term (1-2 weeks). Aliquot and store at -20Degree C or-80Degree C. Avoid repeated freeze / thaw cycles.
Forschungsgebiet CD Antigene, Oberflächenrezeptoren der Immunzellen , Zellzyklus, Gerinnung
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27)", Typ "Antikörper" finden
Wirte Kaninchen (20), Maus (6)
Reaktivitäten Human (22), Ratte (Rattus) (12), Maus (8), Rind (Kuh) (7), Hund (6), Huhn (4), Schimpanse (3), Xenopus laevis (2)
Applikationen Western Blot (WB) (24), Enzyme Immunoassay (EIA) (11), Immunpräzipitation (IP) (7), ELISA (6), Immunhistochemie (IHC) (3), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), Immunfluoreszenz (IF) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
Epitope AA 422-430 (1), N-Term (1), pS427 (1), pSer427 (1), pT244 (1), pThr244 (1)