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Antikörper
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anti-Speedy Homolog A (Xenopus Laevis) (SPDYA) Antikörper
Speedy Homolog A (Xenopus Laevis) (SPDYA) Antikörper
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| Synonyme |
GS4, Spdy1, 4921517J08Rik, 4930548B21Rik, Gs4, SPY1, SPDY1, RINGO3, MGC57218, MGC110856, RINGO, MGC101624, zgc:101624 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN250950 |
| Menge |
0.1 ml (1.1 mg/ml) (Varianten) |
| Preis |
360,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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Speedy-1 / RINGO A
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Gen-ID
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245711, 70891
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Swiss-Prot
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Q5MJ70
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Immunogen
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A synthetic peptide made to a C-terminal region of the human Speedy protein (withinresidues 200-286). This immunogen is conserved in both isoforms 1 and 2. [Swiss-ProtQ5MJ69].
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Beschreibung
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Speedy/Ringo (Spy1) regulates the G1/S phase transition of the cell cycle by bindingand activating CDC2, CDK2 and CDKN1B/KIP1. It mediates cell survival during theDNA damage process through activation of CDK2. Alternate Names: anti-Speedy A isoform antibody, anti-SPDY1 protein antibody, anti-Spy antibody,anti-Ringo antibody, anti-Spy1 antibody.
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Spezifität
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This antibody is specific for Speedy/Ringo protein. Species Reactivity: Mouse. Localization: Nuclear.
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Applikationshinweise
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Positive Controls: Mouse testis lysate
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Konzentration
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1.1 mg/ml
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Buffer
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Tris-citrate/phosphate (pH 7-8). Preservative: 0.1% sodium azide.
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Lagerung
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Store at 4C. Do not freeze.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Publikationen
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Al Sorkhy, Craig, Market et al.: "The cyclin-dependent kinase activator, Spy1A, is targeted for degradation by the ubiquitin ligase NEDD4." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 2617-27, 2009 (PubMed).
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Alternativen zu Antigen "Speedy Homolog A (Xenopus Laevis) (SPDYA)", Typ "Antikörper" finden
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Wirte
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Kaninchen (32)
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Reaktivitäten
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Human (24), Maus (20), Ratte (Rattus) (11), Rind (Kuh) (10), Schwein (7), Hund (6), Huhn (2), Pferd (2), Kaninchen (2)
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Applikationen
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Durchflusszytometrie (FACS) (17), Immunfluoreszenz (IF) (16), Western Blot (WB) (15), ELISA (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1), Immunpräzipitation (IP) (1)
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Konjugate
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Biotin (2), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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AA 176-311 (1)
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