Complement Component C4C (Co4C) Antikörper

Antigen: Complement Component C4C (Co4C)

Klonalität: Polyklonal

Wirt: Huhn

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN249388

Produktbeschreibung

Immunogen: full lenth native protein P0C0L4 purified from human plasma

Format: Liquid

Beschreibung: Complement component C4 consists of three polypeptide chains (alpha,molecular weight 95 kDa, beta, molecular weight 75 kDa and gamma, molecularweight 33 kDa) and is usually present in serum at 200-600 mg/L. It is a protein ofthe classical complement pathway. When activated by C1s, peptide C4a isreleased and the generated C4b binds C2 which is in turn cleaved by C1s toproduce the classical pathway C3 convertase, namely C4b2a. C4b also hasopsonin activity and binds to macrophages and neutrophils via their CR1 receptor.

Spezifität: Predicted reactivity: human.

Anwendungen

Applikationshinweise: Recommended Dilution use at an assay dependent dilution (WB). Additional Information: the IgY fraction is isolated by a two-step PEG precipitation procedure followed byammonium sulphate precipitation .

Buffer: Total IgY fraction at 25.9 mg/ml in 0.9% NaCl, 0.1% sodiumazide

Lagerung: store at 4°C, make aliquots to avoid working with a stock. Please, remember tospin tubes briefly prior to opening them to avoid any losses that might occur fromliquid material adhering to the cap or sides of the tubes.

Beschränkungen: Nur für Forschungszwecke einsetzbar