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Abeta 1-42 Antikörper

Abeta 1-42 Reaktivität: Human WB, ELISA, DB, IL Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN249343
  • Target Alle Abeta 1-42 Antikörper anzeigen
    Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))
    Reaktivität
    • 64
    • 47
    • 40
    • 4
    • 4
    • 4
    • 4
    • 1
    Human
    Wirt
    • 39
    • 27
    • 1
    Kaninchen
    Klonalität
    • 43
    • 24
    Polyklonal
    Konjugat
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Abeta 1-42 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 39
    • 26
    • 18
    • 14
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Dot Blot (DB), Immunolocalization (IL)
    Kreuzreaktivität (Details)
    Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
    Homologie
    bovine, chicken, dog, porcine, rabbit
    Produktmerkmale
    Expected / apparent Molecular Weight of the Antigene: 4.5 kDa
    Aufreinigung
    serum
    Immunogen
    synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
    Top Product
    Discover our top product Abeta 1-42 Primärantikörper
  • Applikationshinweise
    1:1000 (DB), 1:3000 (ELISA), 1-2 μg/mL (IL)
    Kommentare

    the antibody can detect Abeta (1-42), Abeta (1-28) Abeta (1-20) and Abeta (1-17). This product exhibits a low reactivity to monomeric Abeta (1-42) as determined by SDS-PAGE and Western blotting.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    For reconstitution add 100 μL of sterile water.
    Handhabung
    Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
    Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
  • Lindhagen-Persson, Brännström, Vestling, Steinitz, Olofsson: "Amyloid-? oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodies." in: PLoS ONE, Vol. 5, Issue 11, pp. e13928, (2010) (PubMed).

  • Target
    Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))
    Andere Bezeichnung
    Amyloid-beta 42 protein (Abeta (1-42)) (Abeta 1-42 Produkte)
    Synonyme
    amyloid beta precursor protein antikoerper, App antikoerper, APP antikoerper
    Hintergrund
    Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067
    Molekulargewicht
    4.5 kDa
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