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KCNJ8 Antikörper (AA 306-424) (Biotin)

KCNJ8 Reaktivität: Ratte WB, IHC, IF, ICC Wirt: Maus Monoclonal S366-60 Biotin
Produktnummer ABIN2485710
  • Target Alle KCNJ8 Antikörper anzeigen
    KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 306-424
    Reaktivität
    • 39
    • 36
    • 11
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 54
    • 10
    Maus
    Klonalität
    • 54
    • 10
    Monoklonal
    Konjugat
    • 16
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNJ8 Antikörper ist konjugiert mit Biotin
    Applikation
    • 53
    • 28
    • 22
    • 14
    • 13
    • 13
    • 10
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~45 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 306-424 (Cytoplasmic C-terminus) of rat Kir6.1
    Klon
    S366-60
    Isotyp
    IgG2a
    Top Product
    Discover our top product KCNJ8 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:100 dilution of ABIN2485710 was sufficient for detection of Kir6.1 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))
    Andere Bezeichnung
    Kir6.1 (KCNJ8 Produkte)
    Synonyme
    kir6.1 antikoerper, KIR6.1 antikoerper, uKATP-1 antikoerper, AI448900 antikoerper, Kir6.1 antikoerper, gnite antikoerper, slmbr antikoerper, sltr antikoerper, UKATP1 antikoerper, si:dkey-183c2.2 antikoerper, zkir6.1 antikoerper, potassium voltage-gated channel subfamily J member 8 antikoerper, potassium channel, inwardly rectifying subfamily J, member 8 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 8 antikoerper, potassium channel, inwardly rectifying subfamily J, member 8 S homeolog antikoerper, KCNJ8 antikoerper, kcnj8 antikoerper, Kcnj8 antikoerper, kcnj8.S antikoerper
    Hintergrund
    Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family (1-3). This is predominantly detected in fetal and adult hearts, and defects can be associated with J-wave syndromes, a group of heart disorders characterized by early repolarization events (4).
    Gen-ID
    25472
    NCBI Accession
    NP_058795
    UniProt
    Q63664
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