AKT3 Antikörper (AA 119-136)

Produktnummer ABIN2469638

Produktdetails anti-AKT3 Antikörper

Target: AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))

Bindungsspezifität: AA 119-136

Reaktivität: Human, Maus, Ratte, Affe, Hund, Huhn, Rind (Kuh), Schwein, Pferd, Kaninchen, Fledermaus, Gibbon, Gorilla

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AKT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Protein G Column

Immunogen: AKT3 monoclonal antibody was raised against amino acids 119 - 136 of AKT3 (Human).

Klon: 66C1247-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: AKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.05 % BSA, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store AKT3 antibody at 4 °C or -20 °C.

Details zu AKT3

Target: AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))

Andere Bezeichnung: AKT3 (AKT3 Produkte)

Synonyme: MPPH antikoerper, PKB-GAMMA antikoerper, PKBG antikoerper, PRKBG antikoerper, RAC-PK-gamma antikoerper, RAC-gamma antikoerper, STK-2 antikoerper, AI851531 antikoerper, D930002M15Rik antikoerper, Nmf350 antikoerper, Pkbg antikoerper, AKT serine/threonine kinase 3 antikoerper, thymoma viral proto-oncogene 3 antikoerper, v-akt murine thymoma viral oncogene homolog 3b antikoerper, AKT3 antikoerper, Akt3 antikoerper, akt3b antikoerper

Hintergrund: Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.

Gen-ID: 10000

UniProt: Q9Y243

Pathways: PI3K-Akt Signalweg, RTK Signalweg, TLR Signalweg, Hepatitis C, VEGF Signaling