CRYGC Antikörper

Produktnummer ABIN2463921

Produktdetails anti-CRYGC Antikörper

Target: CRYGC (Crystallin, gamma C (CRYGC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYGC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRYGC.

Anwendungsinformationen

Applikationshinweise: CRYGC antibody can be used for detection of CRYGC by ELISA at 1:62500. CRYGC antibody can be used for detection of CRYGC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CRYGC antibody at -20 °C.

Details zu CRYGC

Target: CRYGC (Crystallin, gamma C (CRYGC))

Andere Bezeichnung: CRYGC (CRYGC Produkte)

Synonyme: Cryg antikoerper, Cryg3 antikoerper, Len antikoerper, CCL antikoerper, CRYG3 antikoerper, CTRCT2 antikoerper, Cryg-5 antikoerper, ccl antikoerper, cryg3 antikoerper, MGC84008 antikoerper, CRYGC antikoerper, crystallin, gamma C antikoerper, crystallin gamma C antikoerper, crystallin gamma C L homeolog antikoerper, gamma-crystallin C antikoerper, Crygc antikoerper, CRYGC antikoerper, crygc.L antikoerper, LOC100069179 antikoerper

Hintergrund: Crystallins are the dominant structural components of the vertebrate eye lens.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Molekulargewicht: 21 kDa

Gen-ID: 1420

NCBI Accession: NP_066269

UniProt: P07315