TCEB1 Antikörper

Produktnummer ABIN2463870

Produktdetails anti-TCEB1 Antikörper

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCEB1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCEB1.

Anwendungsinformationen

Applikationshinweise: TCEB1 antibody can be used for detection of TCEB1 by ELISA at 1:7812500. TCEB1 antibody can be used for detection of TCEB1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TCEB1 antibody at -20 °C.

Details zu TCEB1

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Andere Bezeichnung: TCEB1 (TCEB1 Produkte)

Synonyme: 2610043E24Rik antikoerper, 2610301I15Rik antikoerper, AA407206 antikoerper, AI987979 antikoerper, AW049146 antikoerper, SIII antikoerper, eloC antikoerper, TCEB1 antikoerper, fb09f09 antikoerper, wu:fb09f09 antikoerper, zgc:111990 antikoerper, zgc:92635 antikoerper, elongin C antikoerper, elongin C L homeolog antikoerper, transcription elongation factor B (SIII), polypeptide 1b antikoerper, Eloc antikoerper, eloc.L antikoerper, ELOC antikoerper, tceb1b antikoerper

Hintergrund: TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.

Molekulargewicht: 12 kDa

Gen-ID: 6921

NCBI Accession: NP_005639

UniProt: Q15369

Pathways: SARS-CoV-2 Protein Interaktom