TCAP Antikörper

Produktnummer ABIN2463159

Produktdetails anti-TCAP Antikörper

Target: TCAP (Titin-Cap (Telethonin) (TCAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCAP.

Anwendungsinformationen

Applikationshinweise: TCAP antibody can be used for detection of TCAP by ELISA at 1:62500. TCAP antibody can be used for detection of TCAP by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TCAP antibody at -20 °C.

Details zu TCAP

Target: TCAP (Titin-Cap (Telethonin) (TCAP))

Andere Bezeichnung: TCAP (TCAP Produkte)

Synonyme: TCAP antikoerper, CMD1N antikoerper, LGMD2G antikoerper, T-cap antikoerper, TELE antikoerper, telethonin antikoerper, AI503981 antikoerper, AJ223855 antikoerper, titin-cap antikoerper, titin-cap (telethonin) antikoerper, titin-cap S homeolog antikoerper, TCAP antikoerper, tcap antikoerper, tcap.S antikoerper, Tcap antikoerper

Hintergrund: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 19 kDa

Gen-ID: 8557

NCBI Accession: NP_003664

UniProt: O15273