MAT1A Antikörper

Produktnummer ABIN2462397

Produktdetails anti-MAT1A Antikörper

Target: MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAT1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAT1A.

Anwendungsinformationen

Applikationshinweise: MAT1A antibody can be used for detection of MAT1A by ELISA at 1:1562500. MAT1A antibody can be used for detection of MAT1A by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAT1A antibody at -20 °C.

Details zu MAT1A

Target: MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))

Andere Bezeichnung: MAT1A (MAT1A Produkte)

Synonyme: MAT antikoerper, MATA1 antikoerper, SAMS antikoerper, SAMS1 antikoerper, AdoMet antikoerper, SADE antikoerper, SAS antikoerper, AI046368 antikoerper, Ams antikoerper, wu:fi35e01 antikoerper, zgc:55442 antikoerper, methionine adenosyltransferase 1A antikoerper, methionine adenosyltransferase I, alpha antikoerper, MAT1A antikoerper, Mat1a antikoerper, mat1a antikoerper

Hintergrund: MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.

Molekulargewicht: 44 kDa

Gen-ID: 4143

NCBI Accession: NP_000420

UniProt: Q00266

Pathways: Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process