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MTF1 Antikörper

MTF1 Reaktivität: Human, Maus, Hund, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2460357
  • Target Alle MTF1 Antikörper anzeigen
    MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
    Reaktivität
    • 35
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Hund, Ratte
    Wirt
    • 29
    • 7
    Kaninchen
    Klonalität
    • 29
    • 7
    Polyklonal
    Konjugat
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTF1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTF1.
    Top Product
    Discover our top product MTF1 Primärantikörper
  • Applikationshinweise
    MTF1 antibody can be used for detection of MTF1 by ELISA at 1:2500. MTF1 antibody can be used for detection of MTF1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTF1 antibody at -20 °C.
  • Target
    MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
    Andere Bezeichnung
    MTF1 (MTF1 Produkte)
    Synonyme
    MTF-1 antikoerper, MTF1 antikoerper, mtf1 antikoerper, MGC86485 antikoerper, Thyls antikoerper, ZRF antikoerper, metal regulatory transcription factor 1 antikoerper, metal-regulatory transcription factor 1 antikoerper, metal-regulatory transcription factor 1 L homeolog antikoerper, metal response element binding transcription factor 1 antikoerper, MTF1 antikoerper, mtf1 antikoerper, mtf1.L antikoerper, Mtf1 antikoerper
    Hintergrund
    The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
    Molekulargewicht
    81 kDa
    Gen-ID
    4520
    NCBI Accession
    NP_005946
    UniProt
    Q14872
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