FBXW8 Antikörper

Produktnummer ABIN2459935

Produktdetails anti-FBXW8 Antikörper

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXW8.

Anwendungsinformationen

Applikationshinweise: FBXW8 antibody can be used for detection of FBXW8 by ELISA at 1:1562500. FBXW8 antibody can be used for detection of FBXW8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBXW8 antibody at -20 °C.

Details zu FBXW8

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Andere Bezeichnung: FBXW8 (FBXW8 Produkte)

Synonyme: FBW6 antikoerper, FBW8 antikoerper, FBX29 antikoerper, FBXO29 antikoerper, FBXW6 antikoerper, 4930438M06Rik antikoerper, Fbx29 antikoerper, F-box and WD repeat domain containing 8 antikoerper, ring finger protein, transmembrane 2 antikoerper, F-box and WD-40 domain protein 8 antikoerper, FBXW8 antikoerper, Fbxw8 antikoerper, RNFT2 antikoerper

Hintergrund: FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Molekulargewicht: 67 kDa

Gen-ID: 26259

NCBI Accession: NP_699179

UniProt: Q8N3Y1