CYP27A1 Antikörper

Produktnummer ABIN2459496

Produktdetails anti-CYP27A1 Antikörper

Target: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP27A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP27A1.

Anwendungsinformationen

Applikationshinweise: CYP27A1 antibody can be used for detection of CYP27A1 by ELISA at 1:62500. CYP27A1 antibody can be used for detection of CYP27A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP27A1 antibody at -20 °C.

Details zu CYP27A1

Target: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Andere Bezeichnung: CYP27A1 (CYP27A1 Produkte)

Synonyme: CP27 antikoerper, CTX antikoerper, CYP27 antikoerper, Cyp27 antikoerper, P450C27 antikoerper, 1300013A03Rik antikoerper, cytochrome P450 family 27 subfamily A member 1 antikoerper, cytochrome P450, family 27, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 27, subfamily A, polypeptide 1 antikoerper, sterol 26-hydroxylase, mitochondrial antikoerper, CYP27A1 antikoerper, Cyp27a1 antikoerper, cyp27a1 antikoerper

Hintergrund: CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 57 kDa

Gen-ID: 1593

NCBI Accession: NP_000775

UniProt: Q02318