Junctophilin 3 Antikörper

Produktnummer ABIN2459300

Produktdetails anti-Junctophilin 3 Antikörper

Target: Junctophilin 3 (JPH3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Junctophilin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JPH3.

Anwendungsinformationen

Applikationshinweise: JPH3 antibody can be used for detection of JPH3 by ELISA at 1:312500. JPH3 antibody can be used for detection of JPH3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store JPH3 antibody at -20 °C.

Details zu Junctophilin 3

Target: Junctophilin 3 (JPH3)

Andere Bezeichnung: JPH3 (JPH3 Produkte)

Synonyme: CAGL237 antikoerper, HDL2 antikoerper, JP-3 antikoerper, JP3 antikoerper, TNRC22 antikoerper, Jp3 antikoerper, fc26e06 antikoerper, si:ch211-255l14.9 antikoerper, wu:fc26e06 antikoerper, junctophilin 3 antikoerper, JPH3 antikoerper, Jph3 antikoerper, jph3 antikoerper

Hintergrund: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 81 kDa

Gen-ID: 57338

NCBI Accession: NP_065706

UniProt: Q8WXH2