APEH Antikörper

Produktnummer ABIN2459177

Produktdetails anti-APEH Antikörper

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APEH.

Anwendungsinformationen

Applikationshinweise: APEH antibody can be used for detection of APEH by ELISA at 1:312500. APEH antibody can be used for detection of APEH by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store APEH antibody at -20 °C.

Details zu APEH

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Andere Bezeichnung: APEH (APEH Produkte)

Synonyme: AARE antikoerper, ACPH antikoerper, APH antikoerper, D3F15S2 antikoerper, D3S48E antikoerper, DNF15S2 antikoerper, OPH antikoerper, AAP antikoerper, cb5 antikoerper, sb:cb5 antikoerper, wu:fi37d02 antikoerper, acylaminoacyl-peptide hydrolase antikoerper, acylpeptide hydrolase antikoerper, APEH antikoerper, Apeh antikoerper, apeh antikoerper

Hintergrund: APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 81 kDa

Gen-ID: 327

NCBI Accession: NP_001631

UniProt: P13798