LECT1 Antikörper

Produktnummer ABIN2458871

Produktdetails anti-LECT1 Antikörper

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LECT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LECT1.

Anwendungsinformationen

Applikationshinweise: LECT1 antibody can be used for detection of LECT1 by ELISA at 1:1562500. LECT1 antibody can be used for detection of LECT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LECT1 antibody at -20 °C.

Details zu LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Andere Bezeichnung: LECT1 (LECT1 Produkte)

Synonyme: chm1 antikoerper, chm-i antikoerper, bricd3 antikoerper, MGC53801 antikoerper, MGC82444 antikoerper, chondromodulin-I antikoerper, Lect1 antikoerper, BRICD3 antikoerper, CHM-I antikoerper, CHM1 antikoerper, MYETS1 antikoerper, Bricd3 antikoerper, ChM-I antikoerper, Chm-1 antikoerper, chondromodulin L homeolog antikoerper, leukocyte cell derived chemotaxin 1 antikoerper, chondromodulin antikoerper, cnmd.L antikoerper, lect1 antikoerper, CNMD antikoerper, cnmd antikoerper, Cnmd antikoerper

Hintergrund: LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The mature protein promotes chondrocyte growth and inhibits angiogenesis. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 14 kDa

Gen-ID: 11061

NCBI Accession: NP_008946

UniProt: O75829