TPM3 Antikörper

Produktnummer ABIN2458556

Produktdetails anti-TPM3 Antikörper

Target: TPM3 (Tropomyosin 3 (TPM3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPM3.

Anwendungsinformationen

Applikationshinweise: TPM3 antibody can be used for detection of TPM3 by ELISA at 1:312500. TPM3 antibody can be used for detection of TPM3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TPM3 antibody at -20 °C.

Details zu TPM3

Target: TPM3 (Tropomyosin 3 (TPM3))

Andere Bezeichnung: TPM3 (TPM3 Produkte)

Synonyme: CAPM1 antikoerper, CFTD antikoerper, NEM1 antikoerper, OK/SW-cl.5 antikoerper, TM-5 antikoerper, TM3 antikoerper, TM30 antikoerper, TM30nm antikoerper, TM5 antikoerper, TPMsk3 antikoerper, TRK antikoerper, hscp30 antikoerper, cb674 antikoerper, fa17b11 antikoerper, fb83b01 antikoerper, fk41e01 antikoerper, hm:zeh0298 antikoerper, wu:fa17b11 antikoerper, wu:fb83b01 antikoerper, wu:fk41e01 antikoerper, zeh0298 antikoerper, zgc:77592 antikoerper, TPM3 antikoerper, Tm5NM antikoerper, Tpm-5 antikoerper, Tpm5 antikoerper, Trop-5 antikoerper, gamma-TM antikoerper, hTM30nm antikoerper, hTMnm antikoerper, tm3 antikoerper, tpm3 antikoerper, tpm3.L antikoerper, tropomyosin 3 antikoerper, tropomyosin 3, gamma antikoerper, tropomyosin 3 S homeolog antikoerper, TPM3 antikoerper, tpm3 antikoerper, Tpm3 antikoerper, tpm3.S antikoerper

Hintergrund: TPM3 is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer.This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 33 kDa

Gen-ID: 7170

NCBI Accession: NP_705935

UniProt: P06753