Nucleolar Protein 6 Antikörper

Produktnummer ABIN2458545

Produktdetails anti-Nucleolar Protein 6 Antikörper

Target: Nucleolar Protein 6 (NOL6)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nucleolar Protein 6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NOL6.

Anwendungsinformationen

Applikationshinweise: NOL6 antibody can be used for detection of NOL6 by ELISA at 1:1562500. NOL6 antibody can be used for detection of NOL6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NOL6 antibody at -20 °C.

Details zu Nucleolar Protein 6

Target: Nucleolar Protein 6 (NOL6)

Andere Bezeichnung: NOL6 (NOL6 Produkte)

Synonyme: NRAP antikoerper, UTP22 antikoerper, bA311H10.1 antikoerper, nrap antikoerper, utp22 antikoerper, AA410091 antikoerper, Nrap antikoerper, nucleolar protein 6 antikoerper, nucleolar protein 6 L homeolog antikoerper, nucleolar protein family 6 (RNA-associated) antikoerper, NOL6 antikoerper, Nol6 antikoerper, nol6.L antikoerper

Hintergrund: NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.

Molekulargewicht: 127 kDa

Gen-ID: 65083

NCBI Accession: NP_075068

UniProt: Q9H6R4