RUNX1T1 Antikörper (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related))

Details for Product anti-RUNX1T1 Antibody No. ABIN2455775, Anbieter: Anmelden zum Anzeigen
Antigen
  • MTG8
  • si:ch211-232j17.1
  • wu:fi14b07
  • zgc:154044
  • AML1T1
  • CBFA2T1
  • CDR
  • ETO
  • ZMYND2
  • Cbfa2t1h
  • Cbfa2t1
  • runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
  • runx1t1
  • RUNX1T1
  • Runx1t1
Reaktivität
Human
38
18
15
9
7
6
6
5
5
5
4
3
3
1
1
Wirt
Maus
30
8
Klonalität (Klon)
Monoklonal ()
Applikation
Immunofluorescence (IF), Western Blotting (WB)
28
15
6
6
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Full length human recombinant protein of human RUNX1T1(NP_783553) produced in HEK293T cell.
Klon 1H1
Isotyp IgG1
Produktmerkmale Homo sapiens runt-related transcription factor 1, translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3
Reinigung Purified from mouse ascites fluids by affinity chromatography
Andere Bezeichnung RUNX1T1 (RUNX1T1 Antibody Abstract)
Hintergrund This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Molekulargewicht 63 kDa
Gen-ID 862
NCBI Accession NM_175635
HGNC 862
Applikationshinweise WB 1:2000, IF 1:100,
Kommentare

The concentration of the product may vary between diferrent lots.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5-1.0 mg/mL
Buffer PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) antibody (ABIN2455775) Anti-RUNX1T1 mouse monoclonal antibody (ABIN2455775) immunofluorescent staining of CO...
Western Blotting (WB) image for anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) antibody (ABIN2455775) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTR...
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