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RASSF1 Antikörper (AA 1-341)

RASSF1 Reaktivität: Human WB, IF, FACS Wirt: Maus Monoclonal 9F5 unconjugated
Produktnummer ABIN2730557
  • Target Alle RASSF1 Antikörper anzeigen
    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-341
    Reaktivität
    • 50
    • 29
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 5
    • 1
    Maus
    Klonalität
    • 47
    • 4
    Monoklonal
    Konjugat
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RASSF1 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 24
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Produktmerkmale
    Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
    Aufreinigung
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Human recombinant protein fragment corresponding to amino acids 1-341 of human RASSF1(NP_009113) produced in HEK293T cell.
    Klon
    9F5
    Isotyp
    IgG1
    Top Product
    Discover our top product RASSF1 Primärantikörper
  • Applikationshinweise
    WB 1:2000, IF 1:100, FLOW 1:100,
    Kommentare

    The concentration of the product may vary between diferrent lots.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
    Andere Bezeichnung
    RASSF1 (RASSF1 Produkte)
    Synonyme
    RASSF1 antikoerper, zgc:92505 antikoerper, wu:fc17f02 antikoerper, zgc:112224 antikoerper, 123F2 antikoerper, NORE2A antikoerper, RASSF1A antikoerper, RDA32 antikoerper, REH3P21 antikoerper, AA536941 antikoerper, AU044980 antikoerper, Rassf1A antikoerper, Rassf1B antikoerper, Rassf1C antikoerper, NPR2-like, GATOR1 complex subunit antikoerper, Ras association (RalGDS/AF-6) domain family 1 antikoerper, Ras association domain family member 1 antikoerper, putative rassf1 antikoerper, Ras association domain family member 1 L homeolog antikoerper, Ras association (RalGDS/AF-6) domain family member 1 antikoerper, NPRL2 antikoerper, rassf1 antikoerper, RASSF1 antikoerper, Smp_157340 antikoerper, rassf1.L antikoerper, Rassf1 antikoerper
    Hintergrund
    This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
    Molekulargewicht
    38.6 kDa
    Gen-ID
    11186
    NCBI Accession
    NM_007182
    HGNC
    11186
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