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SUMO1 Antikörper (full length) (FITC)

SUMO1 Reaktivität: Human WB, IF, IHC (p) Wirt: Ratte Monoclonal 4D12 FITC
Produktnummer ABIN2452136
  • Target Alle SUMO1 Antikörper anzeigen
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    Bindungsspezifität
    • 15
    • 15
    • 15
    • 15
    • 10
    • 9
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length
    Reaktivität
    • 122
    • 89
    • 67
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 125
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 120
    • 43
    Monoklonal
    Konjugat
    • 72
    • 14
    • 11
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SUMO1 Antikörper ist konjugiert mit FITC
    Applikation
    • 129
    • 70
    • 50
    • 48
    • 40
    • 39
    • 36
    • 26
    • 16
    • 12
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Specific to human, simian, mouse and rat SUMO1.
    Kreuzreaktivität (Details)
    Not tested for other species
    Aufreinigung
    The antibody was produced in serum-free medium and purified by proprietary chromatography procedures under mild conditions and conjugated with FITC.
    Sterilität
    Sterile filtered
    Immunogen
    Recombinant GST-fused human SUMO-1 (full length)
    Klon
    4D12
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product SUMO1 Primärantikörper
  • Applikationshinweise
    1. Immunofluorescence staining: 1/100 dilution
    2. Immunohistochemistry,frozen section: 1/100 dilution
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS (x1), 50 % glycerol. Azide and carrier free.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
  • Ulrich: "The fast-growing business of SUMO chains." in: Molecular cell, Vol. 32, Issue 3, pp. 301-5, (2008) (PubMed).

    Saitoh, Uchimura, Tachibana, Sugahara, Saitoh, Nakao: "In situ SUMOylation analysis reveals a modulatory role of RanBP2 in the nuclear rim and PML bodies." in: Experimental cell research, Vol. 312, Issue 8, pp. 1418-30, (2006) (PubMed).

    Cheng, Bawa, Lee, Gong, Yeh: "Role of desumoylation in the development of prostate cancer." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 8, pp. 667-76, (2006) (PubMed).

    Uchimura, Ichimura, Uwada, Tachibana, Sugahara, Nakao, Saitoh: "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23180-90, (2006) (PubMed).

  • Target
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    Andere Bezeichnung
    SUMO1 (SUMO1 Produkte)
    Synonyme
    DAP1 antikoerper, GMP1 antikoerper, OFC10 antikoerper, PIC1 antikoerper, SENP2 antikoerper, SMT3 antikoerper, SMT3C antikoerper, SMT3H3 antikoerper, UBL1 antikoerper, hm:zeh0670 antikoerper, wu:fb74c02 antikoerper, wu:fd12c02 antikoerper, zgc:65934 antikoerper, zgc:85634 antikoerper, SUMO1 antikoerper, dap1 antikoerper, gmp1 antikoerper, ofc10 antikoerper, pic1 antikoerper, senp2 antikoerper, smt3 antikoerper, smt3c antikoerper, sumo-1 antikoerper, sumo1 antikoerper, ubl1 antikoerper, xsumo-1 antikoerper, xsumo1 antikoerper, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antikoerper, ATSUMO1 antikoerper, F10M23.180 antikoerper, F10M23_180 antikoerper, SMALL UBIQUITIN-LIKE MODIFIER 1 antikoerper, SUM1 antikoerper, SUMO 1 antikoerper, small ubiquitin-like modifier 1 antikoerper, pigSUMO1 antikoerper, SENTRIN antikoerper, SMTP3 antikoerper, SUMO-1 antikoerper, Smt3C antikoerper, Ubl1 antikoerper, small ubiquitin-like modifier 1 antikoerper, small ubiquitin-like modifier 1 S homeolog antikoerper, small ubiquitin-related protein 1 antikoerper, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antikoerper, SMT3 suppressor of mif two 3 homolog 1 (yeast) antikoerper, small ubiquitin-like modifier 1 L homeolog antikoerper, Sumo1 antikoerper, SUMO1 antikoerper, sumo1 antikoerper, sumo1.S antikoerper, sumo-1 antikoerper, sumo1.L antikoerper
    Hintergrund
    SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. Unlike ubiquitination, which targets proteins for degradation, SUMO modification plays a critical role in a number of cellular functions including nucleocytoplasmic transport, gene expression, cell cycle and formation of subnuclear structures such as promyelocytic leukemia (PML) bodies. There are three confirmed SUMO isoforms in human, SUMO1, SUMO2 and SUMO3. SUMO2 /3 show a high degree of similarity to each other and are distinct from SUMO-1. Individual SUMO family members are all targeted to different proteins with diverse biological functions. SUMO-1 is conjugated to RanGAP, PML, p53 and IkappaB-alpha to regulate nuclear trafficking, formation of subnuclear structures, regulation of transcriptional activity and protein stability. SUMO1 is encoded as a 101 aa protein and first Met and C-terminal 4 aa are removed from the preprotein.
    UniProt
    P63165
    Pathways
    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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