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NUP98 Antikörper (AA 1-466)

NUP98 Reaktivität: Human, Maus, Ratte, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB Wirt: Ratte Monoclonal 2H10 unconjugated
Produktnummer ABIN2452066
  • Target Alle NUP98 Antikörper anzeigen
    NUP98 (Nucleoporin 98kDa (NUP98))
    Bindungsspezifität
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-466
    Reaktivität
    • 47
    • 15
    • 11
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Saccharomyces cerevisiae, Schizosaccharomyces pombe
    Wirt
    • 36
    • 11
    • 1
    Ratte
    Klonalität
    • 34
    • 14
    Monoklonal
    Konjugat
    • 38
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NUP98 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 15
    • 12
    • 11
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)
    Kreuzreaktivität (Details)
    This antibody does not react with Tetrahymena.
    Other species have not been tested.
    Aufreinigung
    Purified
    Sterilität
    Sterile filtered
    Immunogen
    Recombinant GST-fused human Nup98 (aa 1-466)
    Klon
    2H10
    Isotyp
    IgG2c kappa
  • Applikationshinweise
    1) Western blotting
    2) Immunocytochemistry
    3) ELISA
    4) Dot blotting

    Properties:
    When injected into the cytoplasm, this antibody accumulates into the nuclear pores of HeLa cells and inhibits nuclear localization of endogenous Ran.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol. Azide- and carrier protein-free.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon arrival centrifuge briefly and store at -20 C.
  • Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

    Fukuhara, Ozaki, Shikata, Katahira, Yoneda, Ogino, Tachibana: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." in: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).

  • Target
    NUP98 (Nucleoporin 98kDa (NUP98))
    Andere Bezeichnung
    Nup98 (NUP98 Produkte)
    Synonyme
    CG10198 antikoerper, CG10201 antikoerper, Dmel\\CG10198 antikoerper, Nup 96 antikoerper, Nup 98 antikoerper, Nup-98 antikoerper, Nup96 antikoerper, Nup98 antikoerper, Nup98-Nup96 antikoerper, Nup98/96 antikoerper, l(3)95BCd antikoerper, nup145 antikoerper, nup98-96 antikoerper, GB12688 antikoerper, NUP98 antikoerper, 4732457F17 antikoerper, AI849286 antikoerper, im:7151238 antikoerper, zgc:113968 antikoerper, zgc:63593 antikoerper, ADIR2 antikoerper, NUP196 antikoerper, NUP96 antikoerper, Nucleoporin 98-96kD antikoerper, nuclear pore complex protein Nup98-Nup96 antikoerper, nucleoporin 98 antikoerper, nucleoporin 98kDa antikoerper, nucleoporin 98 L homeolog antikoerper, Nup98-96 antikoerper, LOC408335 antikoerper, NUP98 antikoerper, LOC587580 antikoerper, Nup98 antikoerper, nup98 antikoerper, nup98.L antikoerper
    Hintergrund
    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. This hybridoma has been established by Prof. T. Tachibana's Lab. at Osaka City Univ.
    UniProt
    Q9HDC8
    Pathways
    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interaktom
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