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NUP153 Antikörper (AA 610-1191)

NUP153 Reaktivität: Ratte WB, ELISA, IF, ICC Wirt: Ratte Monoclonal R4C8 unconjugated
Produktnummer ABIN2452062
  • Target Alle NUP153 Antikörper anzeigen
    NUP153 (Nucleoporin 153kDa (NUP153))
    Bindungsspezifität
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 610-1191
    Reaktivität
    • 40
    • 13
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 39
    • 1
    • 1
    Ratte
    Klonalität
    • 31
    • 10
    Monoklonal
    Konjugat
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser NUP153 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 11
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Specific to human, mouse, rat and monkey Nup153 proteins.
    Kreuzreaktivität (Details)
    Not tested for other species
    Produktmerkmale
    When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.
    Aufreinigung
    Purified
    Sterilität
    Sterile filtered
    Immunogen
    Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)
    Klon
    R4C8
    Isotyp
    IgG2a kappa
  • Applikationshinweise
    1. Western blotting: 160 kDa single band in Hela cell extract
    2. Immunocytochemistry
    3. ELISA
    Other applications have not been tested.

    Additional comments:
    When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
    R4C8 works in immuno-cytochemistry very well.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt aliquot and store at -20 C
  • Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).

    Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).

  • Target
    NUP153 (Nucleoporin 153kDa (NUP153))
    Andere Bezeichnung
    Nup153 (NUP153 Produkte)
    Hintergrund
    The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.
    UniProt
    P49790
    Pathways
    Protein targeting to Nucleus
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