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Antikörper
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anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Antikörper
Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Antikörper
| Antigen |
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| Synonyme |
MACS, 80K-L, PKCSL, PRKCSL, FLJ14368, FLJ90045, KINC, Macs, marcks, MGC89127, MARCKS, MGC137530 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Human (99), Ratte (Rattus) (75), Maus (68), Rind (Kuh) (19), Hund (18), Schwein (18), Kaninchen (17), Huhn (2), Meerschweinchen (1), Säugetiere (1), Zebrafisch (Brachydanio rerio) (1)
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Applikation
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 Alternativen Immunzytochemie (ICC), Immunhistochemie (IHC), Western Blot (WB), Immunfluoreszenz (IF)
Western Blot (WB) (84), Immunfluoreszenz (IF) (58), Durchflusszytometrie (FACS) (21), ELISA (13), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Enzyme Immunoassay (EIA) (11), Immunhistochemie (IHC) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Immunzytochemie (ICC) (5), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN240027 |
| Menge |
100 µl (Varianten) |
| Preis |
429,49 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
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Weitere Bezeichnung
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MARCKS
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Swiss-Prot
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P29966
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Immunogen
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This antibody was made against full length recombinant MARCKS expressed in and purified from E. coli
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Beschreibung
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Gene: MARCKS, Standard Gene Symbol: MARCKS, Family: MARCKS, Synonyms: MARCKS, 80K-L, FLJ14368, FLJ90045, MACS, Myristoylated alanine-rich c-kinase substrate, PKCSL, PRKCSL
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Spezifität
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The MARCKS protein runs at about 80kD on SDS-PAGE gels, although the real molecular is much lower, at about 31.5kD. The reason for this is probably because the protein is extremely rich in acidic residues. Such proteins appear to bind less SDS than the average protein, and so migrate in PAGE more slowly than the normal protein. MARCKS is a major protein of brain, and is concentrated in synapses of neurons. It appears to function in synaptic vesicle cycling and has been shown to bind both actin and calmodulin in vitro. MARCKS belongs to a family of proteins with similar actin and calmodulin binding properties. Deletion of the MARCKS gene in mice results in embryonic brain defects and death.
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Applikationshinweise
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ICC (1:5000), IF (1:500 - 1:1000), IHC (1:5000), WB (1:20000)
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Reinigung
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Antiserum
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Buffer
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Serum.
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Lagerung
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Long term: -20°C, Short term: +4°C
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Forschungsgebiet
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Kardiovaskuläres System
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS)", Typ "Antikörper" finden
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Wirte
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Kaninchen (109), Maus (7), Ratte (2)
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Reaktivitäten
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Human (99), Ratte (Rattus) (75), Maus (68), Rind (Kuh) (19), Hund (18), Schwein (18), Kaninchen (17), Huhn (2), Meerschweinchen (1), Säugetiere (1), Zebrafisch (Brachydanio rerio) (1)
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Applikationen
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Western Blot (WB) (84), Immunfluoreszenz (IF) (58), Durchflusszytometrie (FACS) (21), ELISA (13), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Enzyme Immunoassay (EIA) (11), Immunhistochemie (IHC) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Immunzytochemie (ICC) (5), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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pSer158 (7), pSer162 (7), pSer170 (6), Ab-162 (4), C-Term (4), N-Term (2), pS152/S156 (1), pSer152, pSer156 (1), pSer152/156 (1), pSer159/163 (1), pSer163 (1), phospho (1)
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