Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Antikörper

Antigen: Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR)

Synonyme: SMPR, MPR46, CD-MPR, FLJ32994, CD222, CI-MPR, Mpr300, AI661837, M6P/IGF2R, M6PR, CDMPR, MGC140730, MGC94300, m6pr, MGC68896, MGC130765, zgc:77757, wu:fj81h11, MGC89423, mprd

Klonalität: Polyklonal

Wirt: Ziege

Applikation: ELISA

Produktnummer: ABIN238667

Produktbeschreibung

Weitere Bezeichnung: M6PR

Gen-ID: 4074, 17113 (mouse), 312689 (rat)

Immunogen: KGGDEYDNHCGKEQ

Format: Affinity-purified

Beschreibung: All names and symbols: M6PR, mannose-6-phosphate receptor (cation dependent) , CD-MPR, FLJ32994, MPR46, SMPR, 46-kDa mannose 6-phosphate receptor, Mr 46,000 Man6PR, cation-dependent mannose-6-phosphate receptor. Official Symbol: M6PR. RefSeq number(s): NP_002346.1

Spezifität: Human, Mouse, Rat, Dog, Cow

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Preliminary experiments gave bands at approx 70kDa and 35kDa in Human Lymph Node and Thyroid Gland lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 31.0kDa according to NP_002346.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Zygmunt, McKinnon, Herr et al.: "HCG increases trophoblast migration in vitro via the insulin-like growth factor-II/mannose-6 phosphate receptor." in: Molecular human reproduction, Vol. 11, Issue 4, pp. 261-7, 2005 (PubMed).