Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM) Antikörper

Antigen: Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM)

Synonyme: RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU, MGC166994, RPTPmu, KIAA4044, MGC90724, mKIAA4044, cb984, zgc:110218, PTPRM, ptprm, DKFZp459F233

Klonalität: Polyklonal

Wirt: Ziege

Applikation: ELISA

Produktnummer: ABIN238629

Produktbeschreibung

Weitere Bezeichnung: PTPRM

Gen-ID: 5797

Immunogen: C-KLIRQVDKWQEEYN

Format: Affinity-purified

Beschreibung: All names and symbols: PTPRM, protein tyrosine phosphatase, receptor type, M, MGC166994, PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu, protein tyrosine phosphatase mu, protein tyrosine phosphatase, receptor type, mu polypeptide. Official Symbol: PTPRM. RefSeq number(s): NP_001098714.1, NP_002836.3

Spezifität: This antibody is expected to recognise both reported isoforms (NP_001098714.1 and NP_002836.3). Human, Mouse, Dog

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Preliminary experiments gave bands at approx 110kDa and 16kDa in Rat Retina lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 165kDa according to Human NP_001098714.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Kinasen/Phosphatasen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Aricescu, Hon, Siebold et al.: "Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion." in: The EMBO journal, Vol. 25, Issue 4, pp. 701-12, 2006 (PubMed).