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Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) Antikörper

Antigen

Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C)
Synonyme LIT, DCR1, TRID, CD263, TRAILR3, MGC149501, MGC149502, Dicer, HERNA, KIAA0928, TNFRSF10C
Klonalität Monoklonal (TRAIL-R3-02)
Wirt
Reaktivität
Alternativen

Human
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN238512
Menge 0.1 mg  (1.0 mg/ml)
Preis 230,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper zurück nach oben

Produktmerkmale Synonyms: Decoy receptor 1, TNFRSF10C, DCR1, LIT, TRID, TRAIL receptor 3, TRAIL-R3, Tumor necrosisfactor receptor superfamily member 10C, Decoy TRAIL receptor without death domain,TNF-related apoptosis-inducing ligand receptor 3, Trail receptor without an intracellulardomain, Lymphocyte inhibitor of TRAIL, Antagonist decoy receptor for TRAIL/Apo-2L
Weitere Bezeichnung CD263 / TRAILR3
Swiss-Prot O14798
Immunogen TRAIL-R3 (aa 1-280) - hIgGhc fusion protein.
Kreuzreaktivität Human
Isotyp IgG1  (Passende Sekundärantikörper)
Klon TRAIL-R3-02
Beschreibung TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs toreceptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in manytumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein thatlacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as anegative regulator of apoptotic signaling by competing for binding of TRAIL with deathreceptor 5 (DR5).
Spezifität The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellularmembrane protein expressed mainly on neutrophils. Species: Human. Others not tested.

Anwendungen
Alternativen Sekundärantikörper zurück nach oben

Applikationshinweise Suitable for Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 1.0 mg/ml
Reinigung Azide Free
Buffer PBS, pH 7.4 without preservatives.
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Forschungsgebiet Signaltransduktion, Apoptose/Nekrose
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper zurück nach oben

Alternativen zu Antigen "Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C)", Typ "Antikörper" finden
Wirte Maus (28), Kaninchen (20), Ziege (2)
Reaktivitäten Human (46), Maus (10), Ratte (Rattus) (8)
Applikationen Durchflusszytometrie (FACS) (28), Western Blot (WB) (20), Immunfluoreszenz (IF) (7), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (5), Immunpräzipitation (IP) (5), ELISA (1), ELISA (Detektionsantikörper) (1)
Konjugate PE (6), FITC (5), Biotin (1)