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CD14 Molecule (CD14) Antikörper
| Antigen | CD14 Molecule (CD14) |
| Synonyme | CD14 |
| Klonalität | Monoklonal (MEM-18) |
| Wirt |
Alternativen Maus |
| Reaktivität |
Alternativen Human |
| Produktnummer | ABIN238457 |
| Menge | 0.1 mg (1.0 mg/ml) (Varianten) |
| Preis | 420,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD14 |
| Modifikation | F(ab')2 fragement |
| Swiss-Prot | P08571 |
| Immunogen | A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria |
| Kreuzreaktivität | Human, Affe |
| Isotyp | IgG1 (Passende Sekundärantikörper) |
| Klon | MEM-18 |
| Beschreibung | CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes. |
| Spezifität | The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes, also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64. |
Anwendungen
| Konzentration | 1.0 mg/ml |
| Reinigung | Aff - Purified |
| Buffer | PBS, pH 7.4 without preservatives. |
| Lagerung | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf Life: One year from despatch. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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