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CD14 Molecule (CD14) Antikörper

Antigen

CD14 Molecule (CD14)

Synonyme CD14
Klonalität Monoklonal (MEM-18)
Wirt
Reaktivität
Alternativen

Human

Produktnummer ABIN238457
Menge 0.1 mg  (1.0 mg/ml)  (Varianten)
Preis 420,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD14
Modifikation F(ab')2 fragement
Swiss-Prot P08571
Immunogen A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
Kreuzreaktivität Human, Affe
Isotyp IgG1  (Passende Sekundärantikörper)
Klon MEM-18
Beschreibung CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
Spezifität The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes, also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.

Anwendungen

Konzentration 1.0 mg/ml
Reinigung Aff - Purified
Buffer PBS, pH 7.4 without preservatives.
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf Life: One year from despatch.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CD14 Molecule (CD14)", Typ "Antikörper" finden
Wirte Maus (366), Kaninchen (41), Ratte (35), Ziege (9), Huhn (3)
Reaktivitäten Human (389), Maus (63), Hund (54), Affe (41), Schwein (37), Rind (Kuh) (32), Schaf (28), Cynomolgus (25), Rhesusaffen (25), Kaninchen (24), Primaten (19), Ratte (Rattus) (19), Primate (14), Katze (9), Ziege (9), Pferd (2), Pavian (1), Huhn (1), Schimpanse (1), Llama (1)
Applikationen Durchflusszytometrie (FACS) (370), Western Blot (WB) (71), Immunpräzipitation (IP) (58), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (46), ELISA (37), Immunfluoreszenz (IF) (35), Enzyme Immunoassay (EIA) (32), Funktionale Studien (Func) (32), Immunhistochemie (IHC) (29), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Blockierende Antikörper (Inhibition) (5), ELISA (Detektionsantikörper) (5), Immunzytochemie (ICC) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Radioimmunoassay (RIA) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate FITC (55), PE (46), Biotin (39), APC (27), PerCP,Cy5.5 (10), Pacific Blue (8), RPE (8), Alexa Fluor 488 (6), PE,Cy7 (6), APC,Cy7 (5), Alexa Fluor 647 (5), Cy5.5 (5), Alexa Fluor 700 (4), Cy5 (2), Cy7,PE (2), EFluor 450 (2), EFluor 605NC (2), PE,Cy5 (2), PE,DY590 (2), PE,DY647 (2), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), CF (1), Cy3 (1), Cy7 (1), DY590 (1), DY647 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), PerCP (1), RBITC (1), RPE,Cy5 (1), RPE,Cy5.5 (1)
Epitope C-Term (2), N-Term (2)