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Antikörper
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) Antikörper
Lysosomal-Associated Membrane Protein 1 (LAMP1) Antikörper
| Antigen |
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| Synonyme |
LAMPA, CD107a, LGP120 |
| Klonalität |
Monoklonal (B-T47) |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Durchflusszytometrie (FACS)
Durchflusszytometrie (FACS) (119), Western Blot (WB) (48), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (36), Immunpräzipitation (IP) (33), Immunfluoreszenz (IF) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Immunhistochemie (IHC) (12), Immunzytochemie (ICC) (8), ELISA (2), ELISA (Detektionsantikörper) (2), Enzyme Immunoassay (EIA) (2), Intrazelluläre Durchflusszytometrie (ICFC) (2), Dot Blot (Dot) (1), Immunelektronenmikroskopie (EM) (1)
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| Produktnummer |
ABIN238392 |
| Menge |
0.1 mg (1.0 mg/ml) |
| Preis |
220,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1, CD107Antigen-like Family Member A
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Weitere Bezeichnung
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CD107a / LAMP1
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Swiss-Prot
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P11279
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Immunogen
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U937 human Caucasian hystiocytic lymphoma cell line.
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Kreuzreaktivität
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Human
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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B-T47
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Beschreibung
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CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is amajor constituent of lysosomal membrane, 1-2% of total CD107a is found also on theplasma membrane. The LAMP proteins are involved in lysosome biogenesis and arerequired for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity isobserved in neurones, and in glial cells surrounding senile plaques in Alzheimers diseasecases and is localized mainly in medullary epithelial cells, single macrophages andlymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
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Spezifität
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The antibody B-T47 recognizes CD107a, a 100-120 kDa glycoprotein expressed mainly onlysosomal, but also on the plasma membrane. Species: Human. Others not tested.
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Applikationshinweise
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Suitable for Flow Cytometry and Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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1.0 mg/ml
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Reinigung
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Azide Free
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Buffer
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PBS, pH 7.4 without preservatives.
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Lagerung
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Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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Forschungsgebiet
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CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Lysosomal-Associated Membrane Protein 1 (LAMP1)", Typ "Antikörper" finden
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Wirte
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Maus (86), Ratte (50), Kaninchen (19)
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Reaktivitäten
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Human (90), Maus (59), Ratte (Rattus) (18), Hamster (7), Schwein (6), Primate (2)
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Applikationen
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Durchflusszytometrie (FACS) (119), Western Blot (WB) (48), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (36), Immunpräzipitation (IP) (33), Immunfluoreszenz (IF) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Immunhistochemie (IHC) (12), Immunzytochemie (ICC) (8), ELISA (2), ELISA (Detektionsantikörper) (2), Enzyme Immunoassay (EIA) (2), Intrazelluläre Durchflusszytometrie (ICFC) (2), Dot Blot (Dot) (1), Immunelektronenmikroskopie (EM) (1)
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Konjugate
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FITC (22), PE (22), Biotin (17), APC (12), Alexa Fluor 488 (7), Alexa Fluor 647 (6), Cy5,PE (3), PerCP,Cy5.5 (2), SPRD (2), RPE (1)
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Epitope
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N-Term (2), C-Term (1)
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