Human RING Finger Protein 4 (BMI-1) Antikörper

Antigen: Human RING Finger Protein 4 (BMI-1)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN238069

Produktbeschreibung

Immunogen: Synthetic peptide corresponding to 15 amino acids near the center of human BMI-1 (Genbank accession No. P35226).

Format: Affinity-purified, Liquid

Beschreibung: Rabbit anti BMI-1 Rabbit Antibody to Human RING finger protein 4 (BMI-1)

Spezifität: Reacts with human, mouse and rat BMI-1.

Anwendungen

Applikationshinweise: Suitable for use in Western blot (0.5 ? 1ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Konzentration: Lot specific

Reinigung: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Lagerung: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Alkema, Wiegant, Raap et al.: "Characterization and chromosomal localization of the human proto-oncogene BMI-1." in: Human molecular genetics, Vol. 2, Issue 10, pp. 1597-603, 1994 (PubMed).

Jacobs, Kieboom, Marino et al.: "The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus." in: Nature, Vol. 397, Issue 6715, pp. 164-8, 1999 (PubMed).

Lessard, Sauvageau: "Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells." in: Nature, Vol. 423, Issue 6937, pp. 255-60, 2003 (PubMed).