Human CD29 Antikörper (Biotin)

Antigen: Human CD29

Klonalität: Monoklonal (MEM-101A)

Wirt: Maus

Reaktivität: Human

Konjugat: Biotin

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN234579

Produktbeschreibung

Immunogen: Raji Burkitt?s lymphoma cell line

Format: Liquid

Isotyp: IgG1

Klon: MEM-101A

Beschreibung: MAb to CD29 Monoclonal Antibody to Human CD29 Biotin conjugated Ascites

Spezifität: Reacts with CD29 (integrin beta-1 chain), a 130 kDa single chain type 1 glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits, 1-6). CD29 is broadly expressed on the majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells). Reacts with Human, porcine and canine. Does not react with mouse.

Anwendungen

Applikationshinweise: Suitable for use in Flow cytometry (1:1,000). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Konzentration: Lot specific

Reinigung: Protein A chromatography. The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. Product is free of unconjugated biotin. Source: Ascites

Buffer: PBS, pH 7.4. Preservative: 15mM Sodium azide

Lagerung: Short term store at 2-8°C. Long term, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western Blotting analysis (non-reducing conditions) of isolated peripheral blood lymphocytes of various species using anti-CD29 (MEM-101A). Lane 1: lysate of human PBL. Lane 2: lysate of canine PBL. Lane 3: lysate of porcine PBL

Publikationen

Publikationen: Kim, Cho: "Regulatory role of ginsenoside Rp1, a novel ginsenoside derivative, on CD29-mediated cell adhesion." in: Planta medica, Vol. 75, Issue 4, pp. 316-20, 2009 (PubMed).

Handke, Oelschlegel, Franke et al.: "Hantaan virus triggers TLR3-dependent innate immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 5, pp. 2849-58, 2009 (PubMed).

Lomakina, Knauf, Schultz et al.: "Activation of human neutrophil Mac-1 by anion substitution." in: Blood cells, molecules & diseases, Vol. 42, Issue 3, pp. 177-84, 2009 (PubMed).

Soler, Chapman, Yang et al.: "The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases." in: The Journal of pharmacology and experimental therapeutics, Vol. 330, Issue 3, pp. 864-75, 2009 (PubMed).

Wagner, Bork, Horn et al.: "Aging and replicative senescence have related effects on human stem and progenitor cells." in: PLoS ONE, Vol. 4, Issue 6, pp. e5846, 2009 (PubMed).

Byeon, Choi, Hong et al.: "Inhibitory effect of saponin fraction from Codonopsis lanceolata on immune cell-mediated inflammatory responses." in: Archives of pharmacal research, Vol. 32, Issue 6, pp. 813-22, 2009 (PubMed).

Lee, Lee, Cho: "Cell-permeable ceramides act as novel regulators of U937 cell-cell adhesion mediated by CD29, CD98, and CD147." in: Immunobiology, 2009 (PubMed).