Superoxide Dismutase 1, Soluble (SOD1) Antikörper

Antigen: Superoxide Dismutase 1, Soluble (SOD1)

Synonyme: ALS, SOD, ALS1, IPOA, homodimer, Cu, Zn Sod, Zn-SOD, Cu-Zn SOD, Cu/Zn SOD, Cu/Zn superoxide dismutase, Cu/ZnSOD, CuSOD, CuZn SOD, CuZn-SOD, CuZnSOD, Cu[2+]/Zn[2+]SOD, G, SOD-1, SOD1, To, To-1, cSOD, l(3)108, l(3)68Af', l(3)G, DmelCG11793, CG11793, LOC692639, CU/ZN-SOD, sod1, SODC, DKFZP469M1833

Klonalität: Monoklonal (72B1)

Wirt: Maus

Reaktivität: Human

Applikation: Immunpräzipitation (IP)

Produktnummer: ABIN234155

Produktbeschreibung

Weitere Bezeichnung: Superoxide Dismutase 1 (SOD1)

Immunogen: Recombinant human protein purified from E.coli

Format: Liquid

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 72B1

Beschreibung: Superoxide dismutase (SOD) is an antioxidant enzyme involved in thedefense system against reactive oxygen species (ROS). SOD catalyzesthe dismutation reaction of superoxide radical anion (O2-) to hydrogenperoxide, which is then catalyzed to innocuous O2 and H2O byglutathione peroxidase and catalase. Several classes of SOD have beenidentified. These include intracellular copper, zinc SOD (Cu,Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) andextracellular Cu, Zn-SOD (EC-SOD/SOD-3) (1). SOD1 is found in alleukaryotic species as a homodimeric 32 kDa enzyme containing one eachof Cu and Zn ion per subunit (2). The manganese containing 80 kDatetrameric enzyme SOD2, is located in the mitochondrial matrix in closeproximity to a primary endogenous source of superoxide, themitochondrial respiratory chain (3). SOD3 is a heparin-binding multimer ofdisulfide-linked dimers, primarily expressed in human lungs, vessel wallsand airways (4). SOD4 is a copper chaperone for superoxide dismutase(CCS), which specifically delivers Cu to copper/zinc superoxidedismutase. CCS may activate copper/zinc superoxide dismutase throughdirect insertion of the Cu cofactor.

Synonyme: ALS, SOD, ALS1, IPOA, homodimer, Cu, Zn Sod, Zn-SOD, Cu-Zn SOD, Cu/Zn SOD, Cu/Zn superoxide dismutase, Cu/ZnSOD, CuSOD, CuZn SOD, CuZn-SOD, CuZnSOD, Cu[2+]/Zn[2+]SOD, G, SOD-1, SOD1, To, To-1, cSOD, l(3)108, l(3)68Af', l(3)G, DmelCG11793, CG11793, LOC692639, CU/ZN-SOD, sod1, SODC, DKFZP469M1833

Anwendungen

Applikationshinweise: IP (1-2ul). Positive Control: HeLa.

Buffer: HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50%glycerol

Lagerung: Store for 1 year at -20 degree from date of shipment

Forschungsgebiet: Inflammation, Enzyme, Metabolismus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Superoxide Dismutase 1, Soluble (SOD1) antibody