Basophils Antikörper

Antigen: Basophils

Klonalität: Monoklonal (212H6-16)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Durchflusszytometrie (FACS)

Produktnummer: ABIN223692

Produktbeschreibung

Immunogen: enrichied-human tonsillar pDCs

Isotyp: IgM  (Passende Sekundärantikörper)

Klon: 212H6-16

Beschreibung: Basophils and mast cells are multifunctional hematopoietic effector cells involved in allergic and inflammatory reactions. Immediate allergy is caused by release of chemical mediators by these cell types. In human peripheral blood, 212H6.16 is an antibody specific to a yet non-identified cell-surface structure present on basophils. 212H6 does not induce basophil degranulation, and is therefore a valuable tool for the isolation and study of human basophils. Tonsillar epithelium and skin keratinocytes are also stained by 212H6 in situ: antigen expression in tonsil is restricted to cells lining the epithelial crypts. (Bendriss-Vermare N.et al., Leukocyte Typing VII, White Cell Differenciation Antigen MC13, part 9, myeloid cells, page 425-30, year 2001, Editor Mason).

Spezifität: Human basophils and mast cells

Anwendungen

Applikationshinweise: This monoclonal antibody has been tested in MACS- separation and flow cytometry, ImmunoHistoChemistry: Frozen section..

Buffer: 100 ug in 200ul PBS 50% glycerol

Lagerung: -20°C. KEEP CONTENTS STERILE: no preservative.

Forschungsgebiet: Blutbestandteile

Beschränkungen: Nur für Forschungszwecke einsetzbar