Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (active) Antikörper

Antigen: Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)

Synonyme: CAP4, MACH, MCH5, FLICE, ALPS2B, Casp-8, FLJ17672, MGC78473, Mch5, Caspase-8, MGC92075, caspase-8, zgc:92075, casp8-A, xCaspase-8, CASP8, casp8, DKFZp469A1428

Epitope: active

Klonalität: Monoklonal (C502S)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN223019

Produktbeschreibung

Weitere Bezeichnung: Caspase-8 (Active)

Gen-ID: 12370

Format: Purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: C502S

Beschreibung: 100 ug purified mouse IgG1 (clone C502S). Detects p10 subunit of the active human caspase-8. Tested in Western blotting. Synonyms: Caspase-8 Monoclonal Antibody, Anti-Caspase-8 Polyclonal antibody, Active Caspase-8 antibody, active caspase antibody, caspase-8, active caspase-8, cleaved caspase-8, TNF, Fas, CD95, IETD, caspase-8, anti-caspase-8 Synonyms: Caspase-8 Monoclonal Antibody, Anti-Caspase-8 Polyclonal antibody, Active Caspase-8 antibody, active caspase antibody, caspase-8, active caspase-8, cleaved caspase-8, TNF, Fas, CD95, IETD, caspase-8, anti-caspase-8

Spezifität: Detects p10 subunit of the active human caspase-8

Anwendungen

Applikationshinweise: The antibody can be used for Western blotting (0.5-4 ug/ml) and immunoprecipitation (10 ug/ml). However, the optimal conditions should be determined individually.

Buffer: 100 ug (200 ug/ml) affinity purified antibody in PBS containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Lagerung: Store at -20 o C. For long term storage, aliquot and refreeze at

Forschungsgebiet: Apoptose/Nekrose

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Scarabelli, Stephanou, Pasini et al.: "Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury." in: Circulation research, Vol. 90, Issue 6, pp. 745-8, 2002 (PubMed).

Scarabelli, Pasini, Ferrari et al.: "Warm blood cardioplegic arrest induces mitochondrial-mediated cardiomyocyte apoptosis associated with increased urocortin expression in viable cells." in: The Journal of thoracic and cardiovascular surgery, Vol. 128, Issue 3, pp. 364-71, 2004 (PubMed).

Pattison, Sanbe, Maloyan et al.: "Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure." in: Circulation, Vol. 117, Issue 21, pp. 2743-51, 2008 (PubMed).

Liu, Liu, Lu et al.: "The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells." in: Toxicology and applied pharmacology, Vol. 244, Issue 3, pp. 374-84, 2010 (PubMed).