Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (active) Antikörper

Antigen: Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7)

Synonyme: MCH3, CMH-1, ICE-LAP3, Mch3, mCASP-7, AI314680, ICE-IAP3, caspase-7, xCaspase-7, mch3, cmh-1, ice-lap3, CASP7, LOC100101591

Epitope: active

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunpräzipitation (IP), Immunhistochemie (IHC)

Produktnummer: ABIN222955

Produktbeschreibung

Weitere Bezeichnung: Caspase-7 (Active)

Gen-ID: 840

Immunogen: Synthetic peptide surrounding amino acid 195 of human caspase-7

Format: Affinity-purified

Beschreibung: 100 ug affinity purified rabbit polyclonal antibody. Preferentially recognizes the p20 subunit of active human/mouse/rat caspase-7 and does not recognize the full length caspase-7 or other caspases. Performs well on WB/IP/IHC. Synonyms: Caspase-7 (Active) Polyclonal Ab, Anti-Caspase-7 Polyclonal antibody, Active Caspase-7 antibody, active caspase antibody, caspase-7, anti-caspase-7, DEVD, procaspase-7, active caspase-7, Mch3, ICE/LAP3, CMH1, anti-active caspase-7, anti-cleaved caspase-7 Synonyms: Caspase-7 (Active) Polyclonal Ab, Anti-Caspase-7 Polyclonal antibody, Active Caspase-7 antibody, active caspase antibody, caspase-7, anti-caspase-7, DEVD, procaspase-7, active caspase-7, Mch3, ICE/LAP3, CMH1, anti-active caspase-7, anti-cleaved caspase-7

Spezifität: Preferentially recognizes the p20 subunit of active human/mouse/rat caspase-7 and does not recognize the full length caspase-7 or other caspases

Anwendungen

Applikationshinweise: The antibody can be used for Western blotting (0.5-4 ug/ml), immunoprecipitation (10-20 ug/ml), and immunohistochemistry (10-20 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.

Buffer: 100 ug (0.2 mg/ml) affinity purified rabbit anti-Active caspase-7 antibody in phosphate- buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal

Lagerung: Store at -20 o C. For long term storage, aliquot and freeze at

Forschungsgebiet: Apoptose/Nekrose

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of Jurkat cells inducedwith mM of Camptothecin for hours.

Publikationen

Publikationen: de Vries, Matthijsen, van Bijnen et al.: "Lysophosphatidic acid prevents renal ischemia-reperfusion injury by inhibition of apoptosis and complement activation." in: The American journal of pathology, Vol. 163, Issue 1, pp. 47-56, 2003 (PubMed).

Huang, Masselli, Frisch et al.: "Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29401-13, 2007 (PubMed).

Luyer, Derikx, Beyaert et al.: "High-fat nutrition reduces hepatic damage following exposure to bacterial DNA and hemorrhagic shock." in: Journal of hepatology, Vol. 50, Issue 2, pp. 342-50, 2009 (PubMed).