Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper

Antigen: Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3)

Synonyme: CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788, casp3, xcpp32, CASP3

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN222951

Produktbeschreibung

Weitere Bezeichnung: Caspase-3

Gen-ID: 836

Immunogen: Synthetic peptide corresponding to the C-terminus of caspase-3 large fragment

Format: Affinity-purified

Beschreibung: 100 ug affinity purified rabbit polyclonal antibody. Detects procaspase-3 and the cleaved p20 subunit in Western blot analysis. Reacts with human/mouse/rat. Synonyms: Caspase-3 Polyclonal, Anti-Caspase-3 Polyclonal antibody, Caspase-3 antibody, caspase-antibody, Active caspase-3, caspase-3 antibody, caspase-3, anti-caspase-3, PARP, DEVD, cleaved caspase-3, active caspase-3, procaspase-3 Synonyms: Caspase-3 Polyclonal, Anti-Caspase-3 Polyclonal antibody, Caspase-3 antibody, caspase-antibody, Active caspase-3, caspase-3 antibody, caspase-3, anti-caspase-3, PARP, DEVD, cleaved caspase-3, active caspase-3, procaspase-3

Spezifität: Detects procaspase-3 and the cleaved p20 subunit in Western blot analysis

Synonyme: CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788, casp3, xcpp32, CASP3

Anwendungen

Applikationshinweise: The antibody can be used for Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually.

Buffer: 100 ug (0.2 mg/ml) affinity purified rabbit anti-caspase-3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Lagerung: Store at -20 o C. For long term storage, aliquot and freeze at -70 o C. Avoid repeated freeze/defrost cycles Shelf Life: 12 Months

Forschungsgebiet: Apoptose/Nekrose

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of human caspase-3 with (Lane 1) and without (Lane 2) blocking peptide.

Publikationen

Publikationen: Takebe, Cheng, Fandy et al.: "IMP dehydrogenase inhibitor mycophenolate mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 5, Issue 2, pp. 457-66, 2006 (PubMed).

Atkin, Farg, Turner et al.: "Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1." in: The Journal of biological chemistry, Vol. 281, Issue 40, pp. 30152-65, 2006 (PubMed).

Pietri, Caprini, Mouillet-Richard et al.: "Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells." in: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 28470-9, 2006 (PubMed).

Kiran Kumar, Prabhakara Rao, Noble et al.: "Lead-induced alteration of apoptotic proteins in different regions of adult rat brain." in: Toxicology letters, Vol. 184, Issue 1, pp. 56-60, 2008 (PubMed).

James, Le, Scholey: "INFLUENCE OF GLUCOSAMINE ON GLOMERULAR MESEANGIAL CELL TURNOVER: IMPLICATIONS FOR HYPERGLYCEMIA AND HEXOSAMINE PATHWAY FLUX." in: American journal of physiology. Endocrinology and metabolism, 2009 (PubMed).