Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antikörper

Antigen: Fas (TNFRSF6)-Associated Via Death Domain (FADD)

Synonyme: GIG3, MORT1, MGC8528, Mort1/FADD

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Affe

Applikation: Western Blot (WB), Immunpräzipitation (IP)

Produktnummer: ABIN222894

Produktbeschreibung

Weitere Bezeichnung: FADD

Gen-ID: 8772

Immunogen: Synthetic peptide surrounding amino acid 128 of human FADD

Format: Affinity-purified

Beschreibung: 100 ug affinity purified rabbit polyclonal antibody. Detects ~28 kDa FADD. Reacts with human/mouse/rat/monkey. Applications include WB/IP. Synonyms: FADD, Anti-FADD, FADD antibody, Fas-associated death domain containing protein, MORT1, MORT, TNF-R Synonyms: FADD, Anti-FADD, FADD antibody, Fas-associated death domain containing protein, MORT1, MORT, TNF-R

Spezifität: Detects ~28 kDa FADD

Anwendungen

Applikationshinweise: The antibody can be used for Western blot analysis (0.5-4 ug/ml). Based on researcher's feedback, it can also be used in immunoprecipitation. However, the optimal conditions should be determined individually. Blocking peptide is available separately.

Buffer: 100 ug (0.2 mg/ml) affinity purified rabbit anti-FADD polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Lagerung: Store at -20 o C. For long-term storage, aliquot and freeze at -70 o C. Avoid repeated freeze/defrost cycles Shelf Life: 12 Months

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of FADD expression with Jurkat cell lysates (Lane 1, 2).

Publikationen

Publikationen: Chen, Texada, Duggan et al.: "Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22425-36, 2005 (PubMed).

Piazzolla, Meissl, Kucerova et al.: "Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling." in: The Journal of cell biology, Vol. 171, Issue 6, pp. 1013-22, 2005 (PubMed).

Jin, Ojcius, Sun et al.: "Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways." in: Infection and immunity, Vol. 77, Issue 2, pp. 799-809, 2009 (PubMed).