BCL2-Associated X Protein (BAX) Antikörper

Antigen: BCL2-Associated X Protein (BAX)

Synonyme: BCL2L4, bax, fj16e01, wu:fc50b10, wu:fj16e01, BAX, bax-A, xBax, xlbax, MGC76049, BAX-ALPHA

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunpräzipitation (IP)

Produktnummer: ABIN222887

Produktbeschreibung

Weitere Bezeichnung: Bax

Gen-ID: 581

Immunogen: Synthetic peptide corresponding to amino acids near the N- terminus of human Bax

Format: Affinity-purified

Beschreibung: 100 ug Immunoaffinity purified rabbit polyclonal antibody. Detects 21 kDa Bax in human/mouse/rat samples. Tested in Western blot analysis/immunoprecipitation. Synonyms: Bax Polyclonal Ab, Anti-Bax antibody, Bax polyclonal antibody, apoptosis, Anti-Bax, Bax, bcl-2, Bcl, Bak, Bcl-x, Synonyms: Bax Polyclonal Ab, Anti-Bax antibody, Bax polyclonal antibody, apoptosis, Anti-Bax, Bax, bcl-2, Bcl, Bak, Bcl-x,

Spezifität: Detects 21 kDa Bax in human/mouse/rat samples

Anwendungen

Applikationshinweise: The antibody can be used for Western blot analysis (0.5-4 ug/ml). Based on researchers feedback, it can also be used in immunoprecipitation (10-20 ug/ml). However, the optimal conditions should be determined individually.

Buffer: 100 ug (0.5 mg/ml) affinity purified rabbit anti-Bax polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Lagerung: Store at -20 o C. For long term storage, aliquot and freeze at -70 o C. Avoid repeated freeze/defrost cycles Shelf Life: 12 Months

Forschungsgebiet: Apoptose/Nekrose

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of Bax expression in rat kidney tissue lysate.

Publikationen

Publikationen: Kim, Zhang, Hitomi et al.: "Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL." in: Human molecular genetics, Vol. 15, Issue 11, pp. 1826-34, 2006 (PubMed).

Maity, Bindu, Choubey et al.: "Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathways with concurrent induction of mucosal cell renewal." in: The Journal of biological chemistry, Vol. 283, Issue 21, pp. 14391-401, 2008 (PubMed).

Jafari Anarkooli, Sankian, Vahedi et al.: "Evaluation of insulin and ascorbic acid effects on expression of Bcl-2 family proteins and caspase-3 activity in hippocampus of STZ-induced diabetic rats." in: Cellular and molecular neurobiology, Vol. 29, Issue 1, pp. 133-40, 2009 (PubMed).

Mousavi, Tavakkol-Afshari, Brook et al.: "Direct toxicity of Rose Bengal in MCF-7 cell line: role of apoptosis." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 47, Issue 4, pp. 855-9, 2009 (PubMed).