Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper

Antigen: Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3)

Synonyme: CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788, casp3, xcpp32, CASP3

Klonalität: Monoklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN222869

Produktbeschreibung

Weitere Bezeichnung: Caspase-3

Gen-ID: 836

Immunogen: Recombinant human Caspase-3

Format: Purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Beschreibung: 100 ug purified mouse monoclonal antibody (Mouse IgG1. Clone C33). Detects both procaspase-3 and the cleaved fragments of active caspase-3 in human and mouse sample. Performs well in WB. Synonyms: Caspase-3 Monoclonal Antibody, Anti-Caspase-3 monoclonal antibody, caspase antibody, Active caspase-3, caspase-3 antibody, caspase-3, anti-caspase-3, PARP, DEVD, cleaved caspase-3, active caspase-3, procaspase-3 Synonyms: Caspase-3 Monoclonal Antibody, Anti-Caspase-3 monoclonal antibody, caspase antibody, Active caspase-3, caspase-3 antibody, caspase-3, anti-caspase-3, PARP, DEVD, cleaved caspase-3, active caspase-3, procaspase-3

Spezifität: Detects both procaspase-3 and the cleaved fragments of active caspase-3 in human and mouse sample

Synonyme: CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788, casp3, xcpp32, CASP3

Anwendungen

Applikationshinweise: Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually.

Buffer: 100 ug (200 ug/ml) in PBS containing 50% glycerol, 0.5 mg/ml BSA and 0.01% thimerosal.

Lagerung: Store at -20 o C. For long term storage, aliquot and refreeze at

Forschungsgebiet: Apoptose/Nekrose

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of caspase-3 expression in HeLa cells treated with camptothecin (2 um)

Publikationen

Publikationen: Ahmed, Alcock, Chendil et al.: "Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2." in: The Journal of biological chemistry, Vol. 277, Issue 3, pp. 2234-46, 2002 (PubMed).

Atkin, Farg, Turner et al.: "Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1." in: The Journal of biological chemistry, Vol. 281, Issue 40, pp. 30152-65, 2006 (PubMed).

Pietri, Caprini, Mouillet-Richard et al.: "Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells." in: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 28470-9, 2006 (PubMed).

El Golli Bennour, Rodriguez-Enfedaque, Bouaziz et al.: "Toxicities induced in cultured human hepatocarcinoma cells exposed to ochratoxin A: oxidative stress and apoptosis status." in: Journal of biochemical and molecular toxicology, Vol. 23, Issue 2, pp. 87-96, 2009 (PubMed).