Nephrin Antikörper (AA 451-550) (Alexa Fluor 647)

Produktnummer ABIN2177861

Produktdetails anti-Nephrin Antikörper (Alexa Fluor 647)

Target: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Bindungsspezifität: AA 451-550

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nephrin Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität: Human

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nephrin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Nephrin Antikörper (Alexa Fluor 647) (ABIN2177861)

Fu, Guo, Wang, Huang, Jin, Hu, Chen, Xu, Zhou, Zhao, Sung, Wang, Gaskin, Yang, Fu: "Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 69, Issue 8, pp. 1636-1646, (2017) (PubMed).

Details zu Nephrin

Target: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Andere Bezeichnung: Nephrin (NPHS1 Produkte)

Synonyme: NPHS1 antikoerper, nphs1l antikoerper, nphs1 antikoerper, CNF antikoerper, NPHN antikoerper, nephrin antikoerper, NephrinB antikoerper, NPHS1, nephrin antikoerper, nephrosis 1, congenital, Finnish type (nephrin) antikoerper, NPHS1 nephrin S homeolog antikoerper, nephrin antikoerper, NPHS1 nephrin antikoerper, nephrosis 1, nephrin antikoerper, NPHS1 antikoerper, nphs1 antikoerper, nphs1.S antikoerper, LOC5579127 antikoerper, Nphs1 antikoerper

Hintergrund:

Synonyms: CNF, NPHN, nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1

Background: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).

Gen-ID: 4868

UniProt: O60500

Pathways: Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development