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CSF2RA Antikörper

CSF2RA Reaktivität: Human WB, IP, FACS, IHC (fro), CyTOF Wirt: Maus Monoclonal 4H1 unconjugated
Produktnummer ABIN1981902
  • Target Alle CSF2RA Antikörper anzeigen
    CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
    Reaktivität
    • 50
    • 11
    • 3
    Human
    Wirt
    • 45
    • 10
    Maus
    Klonalität
    • 46
    • 9
    Monoklonal
    Konjugat
    • 27
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CSF2RA Antikörper ist unkonjugiert
    Applikation
    • 36
    • 23
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytometry by Time of Flight (CyTOF)
    Spezifität
    The mouse monoclonal antibody 4H1 recognizes an extracellular epitope of human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    CD116-transfected COS cells
    Klon
    4H1
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CSF2RA Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze. Do not use after expiration date stamped on vial label.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Schwarzmaier, Foell, Weinhage, Varga, Däbritz: "Peripheral monocyte functions and activation in patients with quiescent Crohn's disease." in: PLoS ONE, Vol. 8, Issue 4, pp. e62761, (2013) (PubMed).

    Koba, Haruta, Matsunaga, Matsumura, Haga, Sasaki, Ikeda, Takamatsu, Nishimura, Senju: "Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-? against peritoneally disseminated cancer in xenograft models." in: PLoS ONE, Vol. 8, Issue 6, pp. e67567, (2013) (PubMed).

    Huntington, Legrand, Alves, Jaron, Weijer, Plet, Corcuff, Mortier, Jacques, Spits, Di Santo: "IL-15 trans-presentation promotes human NK cell development and differentiation in vivo." in: The Journal of experimental medicine, Vol. 206, Issue 1, pp. 25-34, (2009) (PubMed).

  • Target
    CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
    Andere Bezeichnung
    CD116 (CSF2RA Produkte)
    Synonyme
    CD116 antikoerper, CDw116 antikoerper, CSF2R antikoerper, CSF2RAX antikoerper, CSF2RAY antikoerper, CSF2RX antikoerper, CSF2RY antikoerper, GM-CSF-R-alpha antikoerper, GMCSFR antikoerper, GMR antikoerper, SMDP4 antikoerper, Csfgmra antikoerper, GM-CSF-Ra antikoerper, GM-CSFR antikoerper, colony stimulating factor 2 receptor, alpha antikoerper, colony stimulating factor 2 receptor alpha subunit antikoerper, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antikoerper, CSF2RA antikoerper, Csf2ra antikoerper
    Hintergrund
    Colony stimulating factor 2 receptor alpha subunit,CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5- receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.,CSF2RA, GMR, CSF2R, SMDP4, GMCSFR
    Gen-ID
    1438
    UniProt
    P15509
    Pathways
    JAK-STAT Signalweg
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