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Paxillin Antikörper (Tyr118)

PXN Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN197279
  • Target Alle Paxillin (PXN) Antikörper anzeigen
    Paxillin (PXN)
    Bindungsspezifität
    • 32
    • 26
    • 17
    • 16
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr118
    Reaktivität
    • 206
    • 111
    • 79
    • 23
    • 11
    • 9
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 191
    • 34
    • 1
    Kaninchen
    Klonalität
    • 176
    • 50
    Polyklonal
    Konjugat
    • 129
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Dieser Paxillin Antikörper ist unkonjugiert
    Applikation
    • 174
    • 67
    • 41
    • 41
    • 40
    • 33
    • 27
    • 25
    • 25
    • 14
    • 14
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Sequenz
    H-V-YP-S-F
    Spezifität
    This antibody detects endogenous levels of total Paxillin protein.
    Aufreinigung
    Affinity-chromatography using epitope-specific immunogen
    Immunogen
    Synthesized non-phosphopeptide derived from human Paxillin around the phosphorylation site of tyrosine 118
    Top Product
    Discover our top product PXN Primärantikörper
  • Applikationshinweise
    WB: 1: 500-1: 1000. IHC: 1: 50-1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store (in aliquots) at -20 °C.
  • Target
    Paxillin (PXN)
    Andere Bezeichnung
    Paxillin / PXN (PXN Produkte)
    Synonyme
    AW108311 antikoerper, AW123232 antikoerper, Pax antikoerper, CG18061 antikoerper, CG18576 antikoerper, CG31794 antikoerper, CT40481 antikoerper, CT42454 antikoerper, DPaxillin antikoerper, DPxn antikoerper, DPxn37 antikoerper, Dmel\\CG31794 antikoerper, Dpax antikoerper, DpaxA antikoerper, PDLP antikoerper, dPax antikoerper, pax antikoerper, wu:fw71f12 antikoerper, PXN antikoerper, LOC100220858 antikoerper, paxillin antikoerper, Paxillin antikoerper, paxillin S homeolog antikoerper, paxillin a antikoerper, PXN antikoerper, Pxn antikoerper, Pax antikoerper, pxn.S antikoerper, pxna antikoerper, LOC696336 antikoerper, pxn antikoerper
    Hintergrund
    Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691
    Gen-ID
    5829
    NCBI Accession
    NP_001074324
    UniProt
    P49023
    Pathways
    MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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