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Cytokeratin 18 Antikörper (pSer33)

KRT18 Reaktivität: Human IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN197077
  • Target Alle Cytokeratin 18 (KRT18) Antikörper anzeigen
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Bindungsspezifität
    • 25
    • 16
    • 15
    • 12
    • 12
    • 11
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer33
    Reaktivität
    • 255
    • 151
    • 112
    • 44
    • 35
    • 28
    • 25
    • 21
    • 19
    • 18
    • 17
    • 14
    • 14
    • 14
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 165
    • 125
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 151
    • 144
    Polyklonal
    Konjugat
    • 145
    • 26
    • 22
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Cytokeratin 18 Antikörper ist unkonjugiert
    Applikation
    • 217
    • 100
    • 84
    • 80
    • 74
    • 60
    • 54
    • 40
    • 39
    • 27
    • 26
    • 19
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Keratin 18 antibody detects endogenous levels of Keratin 18 only when phosphorylated at serine 33.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human Keratin 18 around the phosphorylation site of serine 33 (A-A-SP-V-Y).
    Top Product
    Discover our top product KRT18 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry: 1: 50approx. 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
  • Target
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Andere Bezeichnung
    Cytokeratin 18 (KRT18 Produkte)
    Synonyme
    CK18 antikoerper, K18 antikoerper, Krt1-18 antikoerper, CYK18 antikoerper, DreK18 antikoerper, cb83 antikoerper, dapk1 antikoerper, sb:cb83 antikoerper, wu:fa13f02 antikoerper, wu:fb36b04 antikoerper, krt18 antikoerper, MGC64569 antikoerper, MGC75922 antikoerper, KRT18 antikoerper, CK-18-A antikoerper, K18-A antikoerper, NC-11 antikoerper, cyk18 antikoerper, k18 antikoerper, krt18-a antikoerper, krt18-b antikoerper, krt18a antikoerper, xkendob antikoerper, keratin 18 antikoerper, keratin 18, type I L homeolog antikoerper, keratin 18, type I antikoerper, keratin, type I cytoskeletal 18 antikoerper, K18, simple type I keratin antikoerper, Keratin, type I cytoskeletal 18 antikoerper, keratin 18, type I S homeolog antikoerper, Krt18 antikoerper, KRT18 antikoerper, krt18 antikoerper, krt18.L antikoerper, LOC700569 antikoerper, LOC100136778 antikoerper, k1c18 antikoerper, LOC100008885 antikoerper, krt18.S antikoerper
    Hintergrund
    Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
    Gen-ID
    3875
    NCBI Accession
    NP_000215
    UniProt
    P05783
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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