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EIF2S1 Antikörper (pSer51)

EIF2S1 Reaktivität: Human, Ratte, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN197046
  • Target Alle EIF2S1 Antikörper anzeigen
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Bindungsspezifität
    • 19
    • 9
    • 8
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer51
    Reaktivität
    • 71
    • 42
    • 32
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 75
    • 11
    • 2
    Kaninchen
    Klonalität
    • 71
    • 17
    Polyklonal
    Konjugat
    • 54
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EIF2S1 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 37
    • 32
    • 30
    • 19
    • 13
    • 13
    • 12
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of eIF2A only when phosphorylated at Serine 51.
    Aufreinigung
    Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Synthetic phosphopeptide derived from Human eIF2A around the phosphorylation site of Serine 51 (E-L-SP-R-R).
    Top Product
    Discover our top product EIF2S1 Primärantikörper
  • Applikationshinweise
    Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Andere Bezeichnung
    EIF2A / EIF2S1 (EIF2S1 Produkte)
    Synonyme
    EIF-2 antikoerper, EIF-2A antikoerper, EIF-2alpha antikoerper, EIF2 antikoerper, EIF2A antikoerper, Eif2s1 antikoerper, eif2s1l antikoerper, fb36a08 antikoerper, wu:fb36a08 antikoerper, zgc:56510 antikoerper, 0910001O23Rik antikoerper, 2410026C18Rik antikoerper, 35kDa antikoerper, Eif2a antikoerper, eIF2alpha antikoerper, eif2a antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 subunit alpha antikoerper, eukaryotic translation initiation factor 2, subunit 1 alpha a antikoerper, eukaryotic translation initiation factor 2, subunit 1 alpha antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, Eukaryotic translation initiation factor 2 subunit 1 antikoerper, eukaryotic translation initiation factor 2 subunit alpha L homeolog antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2S1 antikoerper, eif2s1a antikoerper, Eif2s1 antikoerper, eif2s1 antikoerper, LOC693063 antikoerper, CNI00230 antikoerper, THAPSDRAFT_105 antikoerper, if2a antikoerper, eif2s1.L antikoerper, eIF-2alpha antikoerper
    Hintergrund
    EIF2 alpha is a 36 kDa protein which is ubiquitously expressed in many cell types. The eIF2 protein, which is composed of three subunits (alpha, beta and gamma), is one of the key molecules in the initiation of translation. In mammalian cells, eIF2 alpha is phosphorylated at serine 51 (human EIF2 alpha, the equivalent residue in mouse is serine 52) by at least two kinases: the haem-controlled repressor (HCR) and the interferon inducible double stranded RNA-dependent protein kinase (PKR). Phosphorylation of eIF2 alpha blocks the GDP-GTP exchange activity of eIF2 beta, resulting in the suppression of protein synthesis. The phosphorylation of eIF2 alpha is an important regulatory process in protein synthesis.Synonyms: EIF2-A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2 alpha
    Gen-ID
    1965
    NCBI Accession
    NP_004085
    UniProt
    P05198
    Pathways
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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