TFAP2A Antikörper (AA 134-166)

Produktnummer ABIN1945094

Produktdetails anti-TFAP2A Antikörper

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Bindungsspezifität: AA 134-166

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, Rat, Sh

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This mouse Tfap2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the Central region of mouse Tfap2a.

Klon: RB43450

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TFAP2A Antikörper (ABIN1945094)

Yahata, Takedatsu, Dunwoodie, Bragança, Swingler, Withington, Hur, Coser, Isselbacher, Bhattacharya, Shioda: "Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells." in: Genomics, Vol. 80, Issue 6, pp. 601-13, (2002) (PubMed).

Meier, Koedood, Philipp, Fontana, Mitchell: "Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis." in: Developmental biology, Vol. 169, Issue 1, pp. 1-14, (1995) (PubMed).

Moser, Pscherer, Bauer, Imhof, Seegers, Kerscher, Buettner: "The complete murine cDNA sequence of the transcription factor AP-2." in: Nucleic acids research, Vol. 21, Issue 20, pp. 4844, (1993) (PubMed).

Mitchell, Timmons, Hébert, Rigby, Tjian: "Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis." in: Genes & development, Vol. 5, Issue 1, pp. 105-19, (1991) (PubMed).

Details zu TFAP2A

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Andere Bezeichnung: Tfap2a (TFAP2A Produkte)

Synonyme: TFAP2A antikoerper, Ap-2 antikoerper, AP-2 antikoerper, AP-2alpha antikoerper, AP2TF antikoerper, BOFS antikoerper, TFAP2 antikoerper, ap2 antikoerper, xap2 antikoerper, XAP-2 antikoerper, ap2tf antikoerper, tfap2 antikoerper, ap-2alpha antikoerper, tfap2alpha antikoerper, cb93 antikoerper, fb83f04 antikoerper, fc31a07 antikoerper, wu:fb83f04 antikoerper, wu:fc31a07 antikoerper, tfap2a-a antikoerper, tcfap2a antikoerper, ap2a antikoerper, AP2alpha antikoerper, Ap2 antikoerper, Ap2tf antikoerper, Tcfap2a antikoerper, AP2 antikoerper, transcription factor AP-2 alpha antikoerper, transcription factor AP-2 antikoerper, tto transcription factor AP-2 alpha antikoerper, to transcription factor AP-2 alpha L homeolog antikoerper, to transcription factor AP-2 alpha S homeolog antikoerper, Transcription factor AP-2 alpha antikoerper, transcription factor AP-2, alpha antikoerper, TFAP2A antikoerper, LOC100302602 antikoerper, tfap2a antikoerper, tfap2a.L antikoerper, tfap2a.S antikoerper, ap2a antikoerper, Tfap2a antikoerper

Hintergrund: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

Molekulargewicht: 47971

Gen-ID: 21418

UniProt: P34056

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism