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PPARA Antikörper (AA 1-468)

PPARA Reaktivität: Human, Maus WB, FACS, IF, IHC (p) Wirt: Maus Monoclonal 1331CT894-186-143 unconjugated
Produktnummer ABIN1944858
  • Target Alle PPARA Antikörper anzeigen
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    Bindungsspezifität
    • 16
    • 16
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-468
    Reaktivität
    • 99
    • 90
    • 67
    • 18
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 102
    • 13
    Maus
    Klonalität
    • 104
    • 11
    Monoklonal
    Konjugat
    • 50
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Dieser PPARA Antikörper ist unkonjugiert
    Applikation
    • 101
    • 45
    • 40
    • 39
    • 39
    • 16
    • 14
    • 12
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
    Klon
    1331CT894-186-143
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product PPARA Primärantikörper
  • Applikationshinweise
    IF: 1:25. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Cho, Lee, Choi, Yang, Tae Hong, Kim, Yoon: "Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha." in: Immunopharmacology and immunotoxicology, Vol. 31, Issue 3, pp. 459-67, (2009) (PubMed).

    Kobayashi, Kodani, Nozawa, Endo, Sawasaki: "DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system." in: FEBS letters, Vol. 582, Issue 18, pp. 2737-44, (2008) (PubMed).

    Tugwood, Aldridge, Lambe, Macdonald, Woodyatt: "Peroxisome proliferator-activated receptors: structures and function." in: Annals of the New York Academy of Sciences, Vol. 804, pp. 252-65, (1997) (PubMed).

    Mukherjee, Jow, Noonan, McDonnell: "Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators." in: The Journal of steroid biochemistry and molecular biology, Vol. 51, Issue 3-4, pp. 157-66, (1995) (PubMed).

  • Target
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    Andere Bezeichnung
    PPARA (PPARA Produkte)
    Synonyme
    NR1C1 antikoerper, PPAR antikoerper, PPARalpha antikoerper, hPPAR antikoerper, LOC100136415 antikoerper, PPARALPHA antikoerper, nr1c1 antikoerper, xPPARalpha antikoerper, xppara antikoerper, 4933429D07Rik antikoerper, AW742785 antikoerper, Nr1c1 antikoerper, PPAR-alpha antikoerper, Ppar antikoerper, peroxisome proliferator activated receptor alpha antikoerper, peroxisome proliferator-activated receptor alpha antikoerper, peroxisome proliferator activated receptor alpha L homeolog antikoerper, PPARA antikoerper, LOC100136415 antikoerper, ppara.L antikoerper, Ppara antikoerper, ppara antikoerper
    Hintergrund
    Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
    Molekulargewicht
    52225
    Gen-ID
    5465
    UniProt
    Q07869
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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